Search for dissertations about: "cellular stress"

Showing result 21 - 25 of 456 swedish dissertations containing the words cellular stress.

  2. 21. Membrane Stress and the Role of GYF Domain Proteins

    Author : Alexander Georgiev; Åke Wieslander; Hana Sychrova; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SYH1; SMY2; YPT6; RIC1; MYR1; processing bodies; vesicular trafficking; lipid bilayer; budding yeast; GYF; membrane stress; mRNA decay; Saccharomyces cerevisiae; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Intracellular membrane trafficking is regulated by a large number of protein complexes and lipids. Blocking of trafficking disrupts normal membrane dynamics and causes membrane stress. READ MORE

  4. 22. Determination of biomarkers for lipid peroxidation and oxidative stress : Development of analytical techniques and methods

    Author : Kristina Claeson Bohnstedt; Bo Karlberg; Niels Heegaard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; capillary electrophoresis; mass spectrometry; electrospray; porous graphitic carbon; oxidative stress; lipid peroxidation; biomarker; malondialdehyde; hydroxynonenal; isoprostane; Analytical chemistry; Analytisk kemi;

    Abstract : Oxidative stress can be defined as a state of disturbance in the pro-oxidant/antioxidant balance in favour of the former, leading to potential damage. Processes associated with oxidative stress involve reactive oxygen species and radicals and can result in elevated levels of oxidatively modified or toxic molecules that can cause cellular malfunction, and even cell death. READ MORE

  5. 23. Amperometric Biosensors for Detection of Analytes in Cellular Models

    Author : Jaime Castillo Leon; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Simultaneous detection; Bienzyme electrode; Amperometric biosensors; Cellular models; Analytisk kemi; Electrochemistry; Elektrokemi;

    Abstract : Various biological problems such as disease mechanisms, drug development and toxicological studies motivated the introduction of cellular models that today also represent an alternative for reducing the use of animals in controversial medical and pharmaceutical experiments. Cells are complex matrices where several processes occur simultaneously. READ MORE

  6. 24. Development of quantitative optical microscopy methods for single cell analysis

    Author : Katarina Logg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein localization; quantitative optical microscopy; live cell imaging; image analysis; cellular stress;

    Abstract : Optical microscopy has brought powerful methods to biological research, in particular the possibility to assay dynamic molecular processes within living individual cells. This thesis deals with various aspects of fluorescence and Raman microscopy, such as the possibility of avoiding cellular damage or stress caused by illumination, how to manipulate single cells for spectroscopic analysis and how to quantify images automatically. READ MORE

  7. 25. Caulobacter crescentus folding machines at the interface of inheritance, cell division, and energy metabolism

    Author : Kristen Schroeder; Kristina Jonas; Pierre Genevaux; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chaperones; DnaK; chaperonin; GroESL; protein quality control; protein folding; stress response; cellular aging; cell division; bacterial respiration; Caulobacter crescentus; molekylär biovetenskap; Molecular Bioscience;

    Abstract : All living cells must perform essential biological processes while monitoring and responding to environmental cues. Bacteria are accessible experimental systems in which to study the function of conserved central processes. READ MORE