Search for dissertations about: "cellular stress"
Showing result 6 - 10 of 456 swedish dissertations containing the words cellular stress.
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6. Mapping ultrastructural effects of proteotoxic stress on S. cerevisiae
Abstract : Cells are the basic building blocks of any living being, whether the organism consists of only one, or many cells. The different cellular components interact with one another to maintain the viability of the cell. An essential element of cells are proteins – peptide chains folded into a specific conformation unique to every protein. READ MORE
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7. Regulated Proteolysis: The Secrets of Lon : Cellular Roles and Stress-dependent Regulation of the Lon Protease
Abstract : Proteolysis is crucial in cells to maintain a functional proteome. It is required for removal of damaged and unfolded proteins during protein quality control, and serves as a mechanism to regulate protein levels through regulated proteolysis. READ MORE
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8. From single-molecule sensing to extracellular vesicles in glioma cells under stress
Abstract : This thesis describes the work I conducted in two different areas, namely biomolecular sensing and quantitative cell biology. The work in the former area was focused on the optimization of plasmonic metamaterials for sensing applications, and in the latter on the characterization of extracellular vesicles released by glioblastoma cells under stress conditions. READ MORE
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9. Regulation of cellular growth and identification of stromal gene signatures in breast cancer
Abstract : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. READ MORE
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10. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling
Abstract : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. READ MORE