Search for dissertations about: "cellular uptake"

Showing result 1 - 5 of 228 swedish dissertations containing the words cellular uptake.

  1. 1. Cellular Dyes and Bioactive Peptides - Cell Membrane Interactions and Cellular Uptake

    Author : Maria Matson Dzebo; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane Interactions; Spectroscopy; Cell-Penetrating Peptides; Bioactive Peptides; Cell Membrane; Confocal Laser Scanning Microscopy; Cellular Uptake; AF-16; Voltage-Sensitive Dyes; Cell Dyes; Antisecretory Factor; Ruthenium Complexes; Isothermal Titration Calorimetry; Flow-Cytometry;

    Abstract : Knowledge about mechanisms behind interactions of molecules with biomembranes and cellular uptake is very important for understanding biological processes and for drug design. The work described in this thesis has focused on interactions of cellular dyes and bioactive peptides with cells and the cell membrane. READ MORE

  2. 2. Cell-penetrating peptides : cellular uptake and biological activities

    University dissertation from Stockholm : Stockholm University

    Author : Anna Elmquist; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Peptides; Peptider;

    Abstract : .... READ MORE

  3. 3. Intracellular Uptake and Membrane Binding of Cell-penetrating Peptides: The Influence of Arginines, Tryptophans and Proteoglycans

    University dissertation from Stockholm : Stockholm University

    Author : Hanna Rydberg; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; membrane-binding; cellular uptake; proteoglycans; tryptophan; arginine-rich peptide;

    Abstract : One of the major limitations in the realization of functional gene therapy is efficient intracellular transport of the therapeutic macromolecules. Amongst several different techniques, cell-penetrating peptides (CPPs) have emerged as promising candidates for this purpose. READ MORE

  4. 4. Cell-penetrating peptides for oligonucleotide delivery : Design and uptake mechanisms

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Staffan Lindberg; Ülo Langel; Arwyn Jones; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; gene therapy; scavenger receptors; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The use of oligonucleotides for gene therapy has the potential to efficiently treat a plethora of diseases with minimal side effects. However, the use of oligonucleotides is hampered by the properties of these molecules, which make it essentially impossible for them to permeate the cellular membrane. READ MORE

  5. 5. Cellular Uptake of Amyloid Forming Proteins Related to Neurodegenerative Disease

    University dissertation from Gothenburg : Chalmers tekniska högskola

    Author : Emelie Vilhelmsson Wesén; [2020]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; Aβ 1-40 ; Aβ 1-42 ; amyloid fibril; confocal microscopy; α-synuclein; flow cytometry; fluorescence; SH-SY5Y; amyloid-β;

    Abstract : Aggregation and deposition of disease-associated protein is a pathological hallmark of several human disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). These diseases are characterized by the formation of amyloid-β (Aβ) and α-synuclein (α-syn) amyloid fibrils, in extracellular and intracellular locations, respectively. READ MORE