Search for dissertations about: "central nervous system CNS"

Showing result 1 - 5 of 330 swedish dissertations containing the words central nervous system CNS.

2. 1. Cyanide and central nervous system : a study with focus on brain dopamine

   Author : Gudrun Cassel; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

   Abstract : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. READ MORE

4. 2. Central nervous system targets for micturition control

   Author : Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

   Abstract : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. READ MORE

5. 3. Nasal administration of compounds active in the central nervous system : Exploring the olfactory system

   Author : Maria Dahlin; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Nasal administration; olfactory pathway; cerebrospinal fluid; autoradiography; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Abstract : The nasal administration of drugs offers advantages over administration by intravenous injection. Drugs can be rapidly absorbed through the nasal mucosa, resulting in a rapid onset of action, and also avoiding degradation in the gastrointestinal tract and first-pass metabolism in the liver. READ MORE

6. 4. Alphaherpesvirus infections of the central nervous system – Biomarkers, diagnostics and antiviral therapy

   Author : Johan Lindström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpesviruses; central nervous system; facial paralysis; cerebrospinal fluid; biomarkers; acyclovir; neurotoxicity; syndromic testing;

   Abstract : Abstract Herpesviruses predate the evolution of humans and are globally ubiquitous. Herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and varicella-zoster virus (VZV) establish latency in neuronal tissue and may cause infections in the central nervous system (CNS). READ MORE

7. 5. Novel Immunotherapies and Immunoregulation in a Chronic Inflammatory Disease of the Central Nervous System

   Author : Shahram Lavasani; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; Djurfysiologi; Animal physiology; probiotics; immunotherapy; CD1; T-cell; CNS; inflammation; EAE; MS; neuropsykologi; neurofysiologi;

   Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS) which is thought to arise from a breakdown of immunological tolerance in CD4 cells. The aim of this thesis is to improve our understanding of regulation mechanisms of T cell-dependent chronic inflammation in the CNS and explore ways to overcome the onset and progression of the disease, which can be an important step forward in the treatment of MS. READ MORE