Search for dissertations about: "cerebral b"

Showing result 1 - 5 of 39 swedish dissertations containing the words cerebral b.

  2. 1. Brain mechanisms in pain regulation

    Author : Karin B Jensen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The subjective sensitivity to pain differs greatly between individuals and neuroimaging has contributed to the understanding of the cerebral mechanisms involved in pain regulation. The descending pain inhibitory circuitry is a well defined cerebral network that enables regulation of afferent nociceptive information. READ MORE

  4. 2. Stroke, Sex and Vascular Receptor Changes in the Brain

    Author : Hilda Ahnstedt; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelin receptors; Cerebral ischemia; sex; estrogen; progesterone; sex differences; human cerebral arteries; endothelin-1; angiotensin II; middle cerebral artery occlusion; extra-cellular signal regulated kinase 1 and 2;

    Abstract : Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. We have demonstrated an increased expression of cerebrovascular contractile receptors in the brain. This is hypothesized to mitigate cerebral blood flow and exacerbate tissue damage after stroke. READ MORE

  5. 3. The role of the complement system in arthritis and stroke

    Author : Max Albert Hietala; Göteborgs universitet; []
    Keywords : complement; C3; factor B; transgenic knockout; arthritis; focal cerebral ischemia;

    Abstract : Complement is part of the innate immune system and functions primarily as a first line of defense against invading microorganisms. It is a complex cascade, which can be activated via three pathways: the classical, alternative and mannan-binding lectin pathway. READ MORE

  6. 4. MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia

    Author : Aida Maddahi; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitogen activated protein kinase; iNOS; Matrix metalloproteinases; IL-1ß; IL-6; TNF-α; Inflammation; Subarachnoid hemorrhage; Middle cerebral artery occlusion;

    Abstract : INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. READ MORE

  7. 5. On receptor changes in cerebral arteries after subarachnoid haemorrhage

    Author : Jacob Hansen-Schwartz; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Pharmacological sciences; subarachnoid haemorrhage; reverse transcriptase polymerase chain reaction; in vitro pharmacology; organ culture; Endothelin receptors; 5-HT receptors;

    Abstract : Overall the aim has been to characterise the in vitro upregulation of the 5-hydroxytryptamine 1B/1D (5-HT(1B/1D)) and endothelin (ET) receptors in the cerebral circulation as well as demonstrating phenotypic changes in a pathophysiological model mimicking subarachnoid haemorrhage. The first part describes receptor upregulation using organ culture of whole vessel segments from both rat and man. READ MORE