Search for dissertations about: "cerebrospinal fluid biomarkers"

Showing result 1 - 5 of 131 swedish dissertations containing the words cerebrospinal fluid biomarkers.

2. 1. Cerebrospinal fluid studies of bipolar disorder

   Author : Anniella Isgren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar disorder; Cerebrospinal fluid; Biomarkers; Pathophysiology; Proteomics; Neuroimmunology; Cytokines;

   Abstract : The pathophysiology of bipolar disorder remains to be elucidated. One approach to studying brain processes is analysis of cerebrospinal fluid (CSF). READ MORE

4. 2. Cerebrospinal fluid biomarkers for differentiating between Alzheimer’s disease and Vascular dementia

   Author : Maria Bjerke; Göteborgs universitet; []
   Keywords : Vascular dementia; Alzheimer s disease; biomarkers; cerebrospinal fluid;

   Abstract : Patients suffering from mild cognitive impairment (MCI) run a higher risk of developing dementia, with Alzheimer’s disease (AD) being the most common form. Vascular dementia (VaD) is proposed to be the second most common dementia entity, and it includes the clinically relatively homogenous subgroup of subcortical vascular dementia (SVD). READ MORE

5. 3. Cerebrospinal fluid peptidomics: discovery of endogenous peptides as biomarkers of Alzheimer's disease

   Author : Karl Hansson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Biomarkers; Mass spectrometry; Cerebrospinal fluid; Liquid Chromatography; Endogenous peptides;

   Abstract : Neurodegenerative diseases (NDs), the most prominent example of which is Alzheimer’s disease (AD), has turned out to be among the greatest challenges for modern medicine. Common characteristics of NDs involve the aggregation of proteins, progressive loss of neuronal cells in specific regions of the central nervous system (CNS) and as a result – cognitive and/or functional decline. READ MORE

6. 4. Search for Biomarkers in ALS and Parkinson's Disease : Positron Emission Tomography and Cerebrospinal Fluid Studies

   Author : Anders Johansson; Håkan Askmark; Lennart Persson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyotrophic lateral sclerosis; ALS; Parkinson’s disease; cerebrospinal fluid; positron emission tomography; vascular endothelial growth factor; fibroblast growth factor 2; proteomics; Fourier transform ion cyclotron resonance mass spectrometry; deprenyl-D2; PIB; FDG; L-[β11C]-DOPA; Neurology; Neurologi; Neurology; neurologi;

   Abstract : New biomarkers are needed to improve knowledge about pathophysiology, in order to provide earlier correct diagnosis and to follow disease progression of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The aim of this thesis was to find new biomarkers for these diseases. READ MORE

7. 5. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease

   Author : Maja Puchades; Göteborgs universitet; []
   Keywords : Alzheimer s disease; cerebrospinal fluid; proteomics; mass spectrometry; biomarkers; synaptic proteins; liquid phase IEF; biomarkers;

   Abstract : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. READ MORE