Search for dissertations about: "cerebrospinal fluid disorders"

Showing result 1 - 5 of 79 swedish dissertations containing the words cerebrospinal fluid disorders.

  2. 1. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders

    Author : Sara Folkesson Hansson; Göteborgs universitet; []
    Keywords : Alzheimer?s disease; frontotemporal dementia; cerebrospinal fluid; neurodegeneration; proteomics; mass spectrometry; prefractionation; protein identification; quantification;

    Abstract : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. READ MORE

  4. 2. Idiopathic Normal Pressure Hydrocephalus : Cerebrospinal Fluid Tap Test and Magnetic Resonance Imaging as Preoperative Prognostic Investigations

    Author : Johan Virhammar; Elna-Marie Larsson; Katarina Laurell; Kristina Giuliana Cesarini; Magnus Tisell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; normal pressure hydrocephalus; NPH; cerebrospinal fluid disorders; dementia; MRI; CSF tap test; CBF; ASL; Neurology; Neurologi; Neurosurgery; Neurokirurgi; Radiologi; Radiology;

    Abstract : Idiopathic normal pressure hydrocephalus (iNPH) is a condition with dilated cerebral ventricles but intracranial pressure within normal limits. The symptoms of gait impairment, cognitive decline and urinary incontinence develop gradually. Treatment with shunt insertion results in improvement in eight out of ten patients. READ MORE

  5. 3. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease

    Author : Maja Puchades; Göteborgs universitet; []
    Keywords : Alzheimer s disease; cerebrospinal fluid; proteomics; mass spectrometry; biomarkers; synaptic proteins; liquid phase IEF; biomarkers;

    Abstract : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. READ MORE

  6. 4. Candidate biomarkers for synaptic pathology: neurogranin, neuroligins and neurexins in neurodegenerative disorders

    Author : Elena Camporesi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synaptic dysfunction; Alzheimer’s disease; Biomarkers; Neurogranin; Neurexins; Neuroligins; Cerebrospinal fluid; Brain tissue;

    Abstract : Synapses are small units through which neurons communicate in the brain. They represent the site of memory formation and cognitive abilities and are thus primarily affected by neurodegenerative diseases such as Alzheimer’s disease (AD), the leading cause of dementia in the elderly population. READ MORE

  7. 5. Biomarkers in Parkinson's disease and related disorders. Diagnostic value of biochemical markers and their relation to disease progression

    Author : Sara Hall; Lund Neurologi; []
    Keywords : Parkinson s disease; Atypical parkinsonism; Cerebrospinal fluid; Dementia;

    Abstract : .... READ MORE