Search for dissertations about: "chaperones"

Showing result 21 - 25 of 88 swedish dissertations containing the word chaperones.

  2. 21. Biophysical Studies of Protein Folding, Aggregation and Interactions with Molecular Chaperones

    Author : Per Hammarström; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The information for a protein to fold correctly into a well defined three-dimensional functional structure is embedded in the primary sequence. Much effort has been devoted to characterize the nature of the unfolded state, since this state represents the starting point of the folding reaction. READ MORE

  4. 22. Structural studies of microbubbles and molecular chaperones using transmission electron microscopy

    Author : Johan Härmark; Philip JB Köck; Hans Hebert; Reinhard Rachel; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transmission electron microscopy; Contrast agent; Microbubble; Polyvinyl alcohol; Single particle analysis; Heat shock protein; Molecular chaperone; Technology and Health; Teknik och hälsa;

    Abstract : Ultrasound contrast agents (CAs) are typically used in clinic for perfusion studies (blood flow through a specific region) and border delineating (differentiate borders between tissue structures) during cardiac imaging. The CAs used during ultrasound imaging usually consist of gas filled microbubbles (MBs) (diameter 1-5 μm) that are injected intravenously into the circulatory system. READ MORE

  5. 23. Proteostasis beyond chaperones - Auxiliary systems in the management of damaged proteins

    Author : Rebecca Josefson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aging; proteostasis; protein quality control; asymmetric inheritance; vesicle trafficking;

    Abstract : Aging entails loss of functionality and increased risk of death, even for unicellular organisms, such as the yeast Saccharomyces cerevisiae. On a cellular level, aging is accompanied by an accumulation of harmful aging factors, e.g. damaged and aggregated proteins. READ MORE

  6. 24. Biochemical insights into the Cyanobacterial Clp protein family of chaperones and proteases

    Author : Fredrik Andersson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  7. 25. Synthesis and biological evaluation of Bicyclic β-Lactams and 2-Pyridinones : Pilicides Targeting Pilus Biogenesis in Pathogenic Bacteria

    Author : Hans Emtenäs; Ulf Nilsson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; β-lactam; 2-pyridinone; 2-pyridone; Meldrum’s acid; Δ2-thiazoline; solid-phase synthesis; microwave assisted synthesis; antibacterial; pili; pilicide; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : New methods have been developed for the synthesis of bicyclic β-lactams and 2-pyridinones by combining acyl Meldrum’s acids and Δ2-thiazolines. The 2-pyridinones were synthesised both in solution using conventional heating or microwave assisted heating as well as by solid supported chemistry. READ MORE