Search for dissertations about: "chemically induced"

Showing result 1 - 5 of 115 swedish dissertations containing the words chemically induced.

  2. 1. Molecular genetic alterations in chemically-induced lymphomas

    Author : Shi-Mei Zhuang; V. Peter Collins; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Lymphoma is one of the most common malignancies in humans. Its incidence has increased rapidly in the past 30 years. However, the molecular mechanisms underlying the development of lymphomas are largely unknown.Environmental carcinogens play an important role in tumorigenesis. READ MORE

  4. 2. Chemically Induced DNA Damage in Extended-term Cultures of Human Lymphocytes

    Author : Maria Andersson; Björn Hellman; Leif Busk; Uppsala universitet; []
    Keywords : Toxicology; Comet assay; DNA-damaging agents; DNA repair; Extended-term Cultures of Human Lymphocytes; Genotoxicity; Induced DNA damage; In vitro; Mouse Lymphoma Cells; Primary Cell Cultures; Reactive Oxygen Species; Toxikologi;

    Abstract : Generation of DNA damage is regarded to be an important initial event in the development cancer. Consequently, a battery of tests have been developed to detect different types of genotoxic effects in order to be able to predict the potential genotoxicity and mutagenicity of chemicals, including both pharmaceutical drugs and various types of environmental and occupational agents, as well as dietary factors. READ MORE

  5. 3. Predictions of manufacturing induced shape distortions : high performance thermoset composites

    Author : J. Magnus Svanberg; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Polymera konstruktionsmaterial; Polymeric Composite Materials;

    Abstract : High performance composites usually consist of continuous fibres and a thermoset matrix. A well-known example is carbon fibre epoxy composites. When this kind of material is cured residual stresses and/or shape distortions are produced owing to thermally and chemically induced volumetric strains. READ MORE

  6. 4. Regulation of p53 and susceptibility to cell death in chemically-induced preneoplastic hepatocytes

    Author : Ilona Silins; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Induction of preneoplastic lesions, termed enzyme-altered foci (EAF), is considered to be an early step in the development of liver cancer. In view of the relatively homogenous properties of the majority of EAF, these lesions are suggested to arise as an adaptive response to toxic stress. READ MORE

  7. 5. Antibiotics and infusion phlebitis. Clinical and experimental studies

    Author : Peter Lanbeck; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; HUVEC; endothelium vascular; Infektioner; ICAM-1; 3H-thymidine incorporation; cloxacillin; dicloxacillin; phlebitis epidemiology; Antibiotics; phlebitis chemically induced;

    Abstract : Intravenous administration of antibiotics is often followed by infusion phlebitis. In this condition are vessel irritation, inflammation and sometimes superficial thrombosis included. In this thesis, the risk for infusion phlebitis for various antibiotics has been evaluated in a clinical study in 550 patients. READ MORE