Search for dissertations about: "chemoattractants"

Showing result 1 - 5 of 29 swedish dissertations containing the word chemoattractants.

  2. 1. Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology

    Author : Yuri Sheikine; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; coronary artery disease; restenosis; chemokines; eicosanoids;

    Abstract : Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel wall. These processes are mediated, among other substances, by molecules belonging to a large family of chemoattractants. READ MORE

  4. 2. Mediator synergism in mast celldependent inflammation : role of histamine for leukocyte recruitment

    Author : Henrik Thorlacius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chemoattractants; dexamethasone; histamine; inflammation; intravital microscopy; mast cells; leukocyte adhesion; leukocyte rolling; microcirculation; mast cells; nitric oxide; leukotrienes; P-selectin.;

    Abstract : The aim of the present thesis was to study functional interactions between histamine and chemotactic mediators, and the role of histamine for leukocyte recruitment in mast cell-dependent inflammation. Leukocyte rolling, adhesion and emigration. READ MORE

  5. 3. Leukocyte rolling and firm adhesion in the microvasculature : functional significance for leukocyte recruitment in inflammation

    Author : Xun Xie; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adhesion molecules; blood flow; chemoattractants; endothelium; flowcytometry; fucoidin; heparin; inflammation; integrins; intravital microscopy; leukocyteadhesion; leukocyte extravasation; leukocyte rolling; meningitis; mesentery; microcirculation; ;

    Abstract : Leukocyte recruitment to tissues is a key component in the inflammatory process. In order for circulating leukocytes to extravasate, they need to interact with vascular endothelium in several sequential steps. READ MORE

  6. 4. Mast Cell Migration in Inflammatory Diseases

    Author : Niclas Olsson; Gunnar Nilsson; Jaroslaw Dastych; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; inflammation; Patologi; Pathology; Patologi;

    Abstract : Mast cells (MCs) are forceful multifunctional effector cells of the immune system. MCs are normally distributed throughout connective and mucosal tissues, but in several pathological conditions accumulation of MCs occur. READ MORE

  7. 5. Pro- and anti-inflammatory regulation of β2 integrin signalling in human neutrophils

    Author : Veronika Brodin Patcha; Eva Särndahl; Emmanuelle Caron; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; inflammation; neutrophils; signalling; integrins; Cell biology; Cellbiologi;

    Abstract : The body is under constant attack from pathogens trying to slip by our immune defence. If the barrier is breached, invading pathogens enter the tissues and cause inflammation. During this process neutrophils, constituting the first line of defence, leave the bloodstream and seek out and kill the invading pathogens. READ MORE