Search for dissertations about: "chemoenzymatic"

Showing result 1 - 5 of 16 swedish dissertations containing the word chemoenzymatic.

  2. 1. Amine Transaminases in Multi-Step One-Pot Reactions

    Author : Mattias Anderson; Per Berglund; Frank Hollmann; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biocatalysis; enzyme; amine transaminase; ω-transaminase; amination; primary amine; chiral amine; chemoenzymatic; green chemistry; synthesis; cascade; Bioteknologi; Biotechnology;

    Abstract : Amine transaminases are enzymes that catalyze the mild and selective formation of primary amines, which are useful building blocks for biologically active compounds and natural products. In order to make the production of these kinds of compounds more efficient from both a practical and an environmental point of view, amine transaminases were incorporated into multi-step one-pot reactions. READ MORE

  4. 2. Chemoenzymatic Resolution in Dynamic Systems : Screening, Classification and Asymmetric Synthesis

    Author : Yan Zhang; Olof Ramström; Sabine Flitsch; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; constitutional dynamic chemistry; dynamic systemic resolution; dynamic kinetic resolution; enzyme catalysis; transesterification; enzyme promiscuity; asymmetric synthesis; pattern recognition; self-inhibition.;

    Abstract : This  thesis  is  divided  into  four  parts,  all  centered  around  Constitutional Dynamic  Chemistry  (CDC)  and  Dynamic  Kinetic  Resolution  (DKR)  using biocatalysts for selective transformations, and their applications in screening of bioactive compounds, organic synthesis, and enzyme classification.   In  part  one,  an  introduction  to  CDC  and  DKR  is  presented,  illustrating  the basic  concepts,  practical  considerations  and  potential  applications  of  such dynamic systems, thus providing the background information for the studies in the following chapters. READ MORE

  5. 3. Chemoenzymatic synthesis of anionic alkyl glycosides

    Author : NGOC NGO; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Alkyl glycosides; laccase; TEMPO; oxidation; cyclodextrin glucanotransferases;

    Abstract : Growing concerns for environmental issues and product safety for users have shifted research interests towards the use of renewable resources and climate-neutral processes. The enzymatic approach having high selectivity under mild reaction conditions is promising, and the nature-originating products are well accepted. READ MORE

  6. 4. Development of novel chemoenzymatic dynamic kinetic resolutions

    Author : Patrik Krumlinde; Stockholms universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  7. 5. Ruthenium-Catalyzed Hydrogen Transfer Reactions : Mechanistic Studies and Chemoenzymatic Dynamic Kinetic Resolutions

    Author : Madeleine Warner; Jan-Erling Bäckvall; Andreas Pfaltz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hydrogen transfer; ruthenium catalysis; kinetic resolution; dynamic kinetic resolution; racemization; asymmetric synthesis; organisk kemi; Organic Chemistry;

    Abstract : The main focus of this thesis lies on transition metal-catalyzed hydrogen transfer reactions. In the first part of the thesis, the mechanism for racemization of sec-alcohols with a ruthenium complex, Ru(CO)2Cl(η5-C5Ph5) was studied. READ MORE