Search for dissertations about: "chemokine"
Showing result 1 - 5 of 279 swedish dissertations containing the word chemokine.
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1. Dysregulated mucosal immune responses in microscopic colitis patients
Abstract : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. READ MORE
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2. Expression and regulation of CCL25 and its role in T cell localization to and function within the small intestine
Abstract : Earlier studies have demonstrated an important role for the chemokine CCL25, and its receptor CCR9, in the generation of the small intestinal lymphocyte compartment. The work in this thesis was aimed at determining how CCL25 is regulated within the small intestinal mucosa, and what potential role it plays in T cell localization to and function within this site. READ MORE
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3. Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells
Abstract : Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. READ MORE
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4. Chemotactic factors in the human follicle at ovulation
Abstract : Ovulation is initiated by the midcycle gonadotropin surge, which leads to a controlled degradation of the follicle wall ending in follicular rupture and oocyte extrusion. The gonadotropins triggers several biochemical and biophysical changes such as vascular alterations, increased proteolytic enzyme activity and leukocyte extravasation, within the preovulatory follicle. READ MORE
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5. Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system
Abstract : Lyme borreliosis (LB) is the most common vector-borne disease in the Northern Hemisphere. The infection is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and it is transmitted to humans by ticks. READ MORE