Search for dissertations about: "chemopreventive"
Showing result 1 - 5 of 8 swedish dissertations containing the word chemopreventive.
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1. Experimental Studies of Ursolic Acid and Alkaline Sphingomyelinase in Colon Cancer and Colitis
Abstract : Sphingomyelin (SM) is a sphingolipid present in all eukaryotic cell membranes. Hydrolysis of SM by sphingomyelinase (SMase) generates ceramide, which has effects on cell-cycle regulation and apoptosis. READ MORE
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2. Estrogen signaling in colon inflammation and colorectal cancer
Abstract : Colorectal cancer (CRC) is the third most deadly form of cancer in the Western world. Although screening efforts have reduced the overall mortality, the incidence is increasing among young adults. READ MORE
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3. Modelling and Simulation to Improve Antimalarial Therapy
Abstract : The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of these drugs, particularly in vulnerable populations like children and pregnant women. READ MORE
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4. Drug repositioning in chemoprevention of colorectal cancer
Abstract : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. READ MORE
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5. Molecular Signatures of Cancer
Abstract : Cancer is an important public health concern in the western world, responsible for around 25% of all deaths. Although improvements have been made in the diagnosis of cancer, treatment of disseminated disease is inefficient, highlighting the need for new and improved methods of diagnosis and therapy. READ MORE