Search for dissertations about: "chlorohydrin"

Found 1 swedish dissertation containing the word chlorohydrin.

2. 1. Asymmetric transformation of ß- and γ-functionalized alcohols : Study of combined ruthenium-catalyzed racemization and enzymatic resolution

   Author : Annika Träff; Jan-Erling Bäckvall; Reko Leino; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Kinetic resolution; dynamic kinetic resolution; kinetic asymmetric transformation; dynamic kinetic asymmetric transformation; enzyme catalysis; racemization; asymmetric synthesis; chlorohydrin; cyano acetate; amino alcohol; metalloenzyme; bifunctional catalytic system; Organic synthesis; Organisk syntes; organisk kemi; Organic Chemistry;

   Abstract : The major part of this thesis describes the asymmetric synthesis of β- and γ-amino alcohols through the combination of ruthenium catalyzed racemization and enzymatic kinetic resolution. The dynamic kinetic resolution, DKR, protocol for chlorohydrins was improved by employing Bäckvall’s catalyst, which is a base activated racemization catalyst, in combination with Burkholderia cepacia lipase. READ MORE