Search for dissertations about: "cholesterol 7a-hydroxylase"

Found 2 swedish dissertations containing the words cholesterol 7a-hydroxylase.

  2. 1. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients

    Author : Carl-Gustaf Hillebrant; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid synthesis; biliary lipids; cholesterol synthesis; cholesterol 7a-hydroxylase; cholesterol synthesis inhibitor; chenodeoxycholic acid; cholestyramine; 7a-hydroxy-4-cholesten-3-one; HMG CoA reductase; lathosterol; lipoproteins; lithocholic acid; plasma apheresis; ursodeoxycholic acid;

    Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE

  4. 2. Studies on the atypical orphan receptor SHP

    Author : Lotta Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nuclear receptors (NRs) comprise the largest family of transcription factors in eukaryotes and play critical roles in nearly every aspect of vertebrate development and adult physiology. In general, they function as transcriptional regulators that when bound to DNA either activate or suppress target gene expression. READ MORE