Search for dissertations about: "chondrosarcoma"

Showing result 1 - 5 of 9 swedish dissertations containing the word chondrosarcoma.

  2. 1. Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma and other cartilage tumors

    Author : Helene Sjögren; Göteborgs universitet; []
    Keywords : Extraskeletal myxoid chondrosarcoma; chondroblastoma; chondrosarcoma; spectral karyotyping SKY ; chromosome translocation; fusion oncogene; cDNA microarray; TEC; EWS; TAF2N; TCF12;

    Abstract : .... READ MORE

  4. 2. Cell cycle genes in chondrosarcoma. Involvement of the Id1 and p16 pathways

    Author : Julia Asp; Göteborgs universitet; []
    Keywords : chondrosarcoma; articular chondrocytes; cell cycle; p16; Id1; helix-loop-helix;

    Abstract : Chondrosarcoma is a malignant, cartilaginous tumour arising from bone. The wide variationin morphology, behaviour and clinical outcome raise the question whether chondrosarcomasare several different but closely related tumours rather than a single entity. READ MORE

  5. 3. The complexity of prognostication in musculoskeletal sarcomas. An analysis of four illustrative entities

    Author : Peter Bergh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sarcoma; surgery; pathology; extraskeletal myxoid chondrosarcoma; synovial sarcoma; chordoma; chondrosarcoma;

    Abstract : Although malignant musculoskeletal tumors are rare, they encompass numerous entities with a wide morphological, clinical and prognostic spectrum. Sarcoma surgery is particularly demanding. Treatment must take into account the lesionís inherent biologic behavior, anatomic location and individual patient factors. READ MORE

  6. 4. Responses of fibroblasts and chondrosarcoma cells to mechanical and chemical stimuli

    Author : Juha Piltti; Mikko Lammi; Jukka Häyrinen; Frank Beier; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rho-kinase inhibition; Y-27632; hypoxia; cyclic stretching; human chondrosarcoma 2 8 cells; chondrocyte phenotype; fibroblasts; proteomics; protein pathway analytics; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Osteoarthritis is an inflammation-related disease that progressively destroys joint cartilage. This disease causes pain and stiffness of the joints, and at advanced stages, limitations to the movement or bending of injured joints. Therefore, it often restricts daily activities and the ability to work. READ MORE

  7. 5. Array based genetic profiling of bone and soft tissue tumors

    Author : Karolin Hansén Nord; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In this thesis, genetic alterations in bone and soft tissue tumors have been investigated with the purpose of identifying regions of importance for tumor development, diagnosis and prognosis. This has primarily been performed by array comparative genomic hybridization analysis and gene expression profiling of cytogenetically analyzed tumors. READ MORE