Search for dissertations about: "chromatin organization"
Showing result 1 - 5 of 62 swedish dissertations containing the words chromatin organization.
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1. Transcription regulation across levels of chromatin organization
Abstract : With advancements in high-throughput sequencing and high-resolution microscopy techniques, the significance of genome organization in transcription regulation is rapidly unveiling. Nonetheless, we are yet far from completely understanding this key relationship. READ MORE
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2. Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function
Abstract : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. READ MORE
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3. The role of nuclear membrane proteins in differentiation and chromatin organization
Abstract : The nuclear envelope, consisting of an outer and an inner nuclear membrane, surrounds the genomic material. The genomic material (chromatin) is highly structured with (transcriptionally inactive) heterochromatin mostly found in the nuclear periphery and (transcriptionally active) euchromatin mostly found in the nuclear interior. READ MORE
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4. Chromatin remodelers and their roles in chromatin organization
Abstract : The DNA in the eukaryotic nucleus is organized into a complex DNA-protein structure called chromatin. The basic repeating unit of chromatin is the nucleosome, which consists of 147 bp of DNA wrapped around a histone protein octamer. READ MORE
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5. The role of nuclear envelope proteins in chromatin organization, differentiation and disease
Abstract : In eukaryotes the genetic material is separated from the cytoplasm by the nuclear envelope (NE), consisting of the outer and inner nuclear membrane, the nuclear lamina and the nuclear pores. The genetic material is highly structured with transcriptionally inactive heterochromatin enriched at the nuclear periphery and transcriptionally active euchromatin in the nuclear interior. READ MORE