Search for dissertations about: "chromatin remodeling"

Showing result 21 - 25 of 53 swedish dissertations containing the words chromatin remodeling.

  2. 21. Dissecting the epigenetic landscapes of hematopoiesis and fission yeast

    Author : Michelle Rönnerblad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The genome of eukaryotic cells is stored in the nucleus as chromatin, a DNA-protein complex that serves to compact and protect the DNA molecules. The basic unit of chromatin is the nucleosome composed of DNA wrapped around a histone protein core. READ MORE

  4. 22. Molecular control of activity - dormancy transitions in Populus

    Author : Madeleine Englund; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Perennials such as woody plants, growing in the high northern part of the earth have to cope with seasonal changes alternating between mild summer and the harsh winter periods. To survive and adapt their reproductive phase to the most favorable environmental conditions trees cycle between periods of active growth during summer and a state of growth arrest during winter, referred to as the activity- dormancy cycle. READ MORE

  5. 23. Studies on nuclear factor 1 binding to nucleosomal DNA

    Author : Patrik Blomquist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : nuclear factor 1; nucleosome; glucocorticoid receptor; triplex DNA; the SWISNF complex; A-tracts; MMTV LTR;

    Abstract : The organisation of DNA into chromatin will influence on transcriptional regulation. The first event in transcriptional activation is the binding of transcription factors to specific binding sites in the regulatory regions of the gene. READ MORE

  6. 24. Remodelling of the cellular environment in Epstein-Barr virus infection

    Author : Simone Callegari; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : For successful infection viruses modify the host cell environment by transcriptional, posttranscriptional or post-translational regulation of cellular signaling pathways. In the work described in this thesis bioinformatics analysis coupled with biochemical validations were used to dissect critical features of these viral strategies in the context of infection by Epstein–Barr virus (EBV), a human herpesvirus associated with lymphoid and epithelial cell tumors. READ MORE

  7. 25. The role of HIF-1alpha in epigenetic regulation of transcription

    Author : Nikola Vojnovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The oxygen level inside cells, determine the amount of HIF protein. By directly being involved in HIF protein turnover rates, through a mechanism, by which, oxygen is utilized as a co-factor, for the PHD enzymes, regulating HIF protein stability. READ MORE