Search for dissertations about: "chromatin structure"

Showing result 1 - 5 of 110 swedish dissertations containing the words chromatin structure.

  1. 1. Chromatin Structure: Nucleosome Formation and Positioning

    Author : Hans R. Widlund; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; centromere; formation; chromatin; nucleosome; telomere;

    Abstract : In all eukaryotic cells the DNA is complexed with a group of highly basic histone proteins forming nucleosomes and higher order chromatin structures. In the nucleosome the DNA is tightly wrapped, almost two turns, around an octamer of histone proteins. READ MORE

  2. 2. DNA-protein complexes : experimental studies of structure and interactions in solution

    Author : Per Hagmar; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA binding domain; methylene blue; flow linear dichroism; recombination protein A; RecA; chromatin structure; recombination; electric linear dichroism; chromatin; glucocorticoid receptor;

    Abstract : .... READ MORE

  3. 3. Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function

    Author : Patrik Asp; Ann-Kristin Östlund Farrants; Anthony Imbalzano; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatin; chromatin remodeling; SWI SNF; ISWI; BRG1; SNF2H; Prp8; RNA; transcription; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. READ MORE

  4. 4. The interplay of transcription and chromatin regulation during embryonic development

    Author : George Hunt; Mattias Mannervik; Eileen Furlong; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription; chromatin; chromatin-modifiers; p300 CBP; Polycomb repression; promoter proximal Pol II pausing; molekylär biovetenskap; Molecular Bioscience;

    Abstract : A fascinating aspect of multicellular development is the production of diverse cell types from an identical DNA genome, which depends on the ability to express different complements of genes across space and time. This thesis tries to address how the genome, within the chromatin structure that envelops it, is regulated to direct this complex process. READ MORE

  5. 5. Chromatin and transcriptome-based integrative approaches to profile functional long noncoding RNAs - A computational approach

    Author : Santhilal Subhash; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Computational biology; Long noncoding RNAs; Chromatin; S-phase; Cell cycle; sperm; Epigenetics; Histone; cancer; oncogene; Tumor suppressor; DNA methylation; Histone modifications; Chromatin remodelers; lncRNAs; lincRNAs;

    Abstract : One of the major hallmarks of cancer is aberrant or uncontrollable cell division, which occurs due to a defective cell cycle process. During the synthesis phase (S-phase) of the cell cycle, before cell division or mitosis phase, the DNA in the cell makes a new copy to pass on genetic information to the daughter cells. READ MORE