Search for dissertations about: "chromosome 8"

Showing result 11 - 15 of 253 swedish dissertations containing the words chromosome 8.

  2. 11. Control of Chromosome and Plasmid Replication in Escherichia coli

    Author : Jan Olsson; Kurt Nordström; Santanu Dasgupta; Måns Ehrenberg; Anders Lobner-Olesen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Abstract : Life is cellular. Cells grow and divide to give two new cells; this process is called the cell cycle. The chromosome in a bacterium is replicated into two identical copies before the cell divides. DNA replication is a fundamental process common to all forms of life. READ MORE

  4. 12. Chromosome aberrations and environmental exposures in acute leukemia

    Author : Ragnhild Rosengren Lindquist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acute leukemia; chromosome 3; chromosome 8; fragile site; occupational exposure; mutagen exposure; case-control study; trisomy; benzene; organic solvent; petroleum; epidemiology; environmental carcinogens; painter; driver;

    Abstract : The aims of this thesis are to evaluate the role of environmental exposures, especially professional exposure to organic solvents and petroleum products in the etiology of acute leukemia and to investigate if there is a correlation between the exposure to a specific leukemogen factor and a clonal chromosome aberration of the leukemic cells. Papers I and II present results of a case-control study of environmental exposures, in all occupations during life-time, medical treatments with medicines, chemotherapy and radiation, tobacco-use and the exposure to chemical compounds in private life in 120 patients with acute leukemia and of 120 controls, matched for age (+ 4 years), residence and sex. READ MORE

  5. 13. The Smc5/6 complex : linking DNA replication with chromosome segregation

    Author : Kristian Jeppsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In order to faithfully propagate the genetic material from one generation to the next, cells need to properly replicate and segregate their chromosomes. The three well-conserved eukaryotic Structural Maintenance of Chromosomes (SMC) protein complexes, cohesin, condensin and the Smc5/6 complex (Smc5/6) organize chromosomes to ensure that the daughter cells receive a full complement of chromosomes. READ MORE

  6. 14. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells

    Author : Philipp Pottmeier; Elena Jazin; Armin Raznahan; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex chromosome; gametolog; x y homolog; male; female; sex differences; sex bias; embryonic stem cells; neurodevelopment; neuronal differentiation; neural stem cells; genetics; neurodevelopmental disorders; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Neuroscience; Neurovetenskap; Medicinsk genetik; Medical Genetics;

    Abstract : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. READ MORE

  7. 15. Cardiovascular Risk Genes in Prevention and Treatment Response

    Author : Viktor Hamrefors; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood pressure treatment; hypertension; statins; dyslipidemia; cardiovascular prevention; cardiovascular genetics; stroke; coronary artery disease; chromosome 9p21; pharmacogenetics; pharmacogenomics;

    Abstract : GENERAL AIM: To investigate how common single-nucleotide-polymorphisms (SNPs) that associate with cardiovascular disease (CVD) could be used in prevention and treatment of CVD. SUBJECTS: Subjects from the population-based Malmö-Diet-and-Cancer-(MDC)-Study (n=30447) and hypertensives from the Nordic-Diltiazem-(NORDIL)-Study (n=10881). READ MORE