Search for dissertations about: "chromosome region 3q21"

Showing result 1 - 5 of 6 swedish dissertations containing the words chromosome region 3q21.

  2. 1. Genetic susceptibility to psoriasis in Sweden

    Author : Fredrik Enlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD80; CD86; joint complaints; linkage analysis; NPL; psoriasis; TDT; chromosome region 3q21;

    Abstract : A common skin disease affecting about 2-3% of the population, psoriasis has an inheritance pattern that is unclear, but most probably many genes are involved in its pathogenesis. Other studies have suggested many susceptibility regions in the genome, but as yet independent studies have replicated only some of these regions located on chromosome 1q, 6p and 17q. READ MORE

  4. 2. Genetic Studies of Psoriasis and Psoriatic Arthritis

    Author : Camilla Friberg; Göteborgs universitet; []
    Keywords : psoriasis; psoriatic arthritis; complex disease; autoimmune disease; linkage analysis; association analysis; PSOR5; 3q21; 5q31-32; SLC22A4; SLC22A5; CSTA; ZNF148; expression;

    Abstract : Psoriasis and psoriatic arthritis are common chronic immune-mediated diseases of the skin and joints. Psoriasis affects approximately 2-3 % of the Caucasian population and about 30 % of all psoriasis patients develop psoriatic arthritis. READ MORE

  5. 3. Genetic studies of atopic dermatitis

    Author : Maria Bradley; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atopic dermatitis; genome-wide linkage analysis; sib pairs; candidate genes; nonparametric linkage;

    Abstract : Known from ancient times, atopic dermatitis is now the most prevalent chronic inflammatory skin disease in Swedish children. This is the result of a marked increase over the past few decades. READ MORE

  6. 4. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

    Author : Marie Karlsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genomic organisation; baculovirus-insect cells; catalytic triad; alfa beta hydrolase fold; tissue distribution; cDNA sequence; lipolysis; adipocyte; monoglyceride lipase; hormone-sensitive lipase; chromosomal localisation; Clinical biology; Klinisk biologi;

    Abstract : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. READ MORE

  7. 5. Genetic mapping and association analysis in multiple sclerosis

    Author : Eva Åkesson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Multiple sclerosis; genetic; linkage; association; susceptibility;

    Abstract : Multiple sclerosis (MS) is a chronic neurological disease. Epidemiological studies have shown evidence for both environmental and genetic involvement of the disease. READ MORE