Search for dissertations about: "chromosome translocation"
Showing result 1 - 5 of 46 swedish dissertations containing the words chromosome translocation.
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1. Development and Application of Human Chromosome 22 Genomic Microarray : Chromosome 22-Associated Disorders Analyzed by Array-Based Comparative Genomic Hybridization
Abstract : The array-based form of comparative genomic hybridization (array-CGH) is a new methodology that has shown to be of significant importance. This thesis focuses on the development of array-CGH with the aim to define candidate regions/genes on chromosome 22 in a wide spectrum of cancer-related conditions. READ MORE
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2. Molecular studies of genetic changes in myxoid and round cell liposarcoma
Abstract : Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. READ MORE
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3. Studies of gene fusions and copy number alterations in salivary and adnexal neoplasms
Abstract : Cancer is a genetic disease caused by the accumulation of genetic changes such as mutations and chromosomal rearrangements. An increasing number of genetic studies of both hematological and solid neoplasms have shown that recurrent chromosome translocations often result in fusion oncogenes. READ MORE
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4. Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma and other cartilage tumors
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5. Studies of PLAG1 and HMGIC fusion oncogenes in human tumors
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