Search for dissertations about: "chronic constriction injury"

Found 3 swedish dissertations containing the words chronic constriction injury.

  1. 1. Structure and function of trigeminal primary sensory neurons after peripheral nerve injury

    Author : Ulf Bongenhielm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ankyrinG; chronic constriction injury; electron microscopy; electrophysiology; hyperexcitability; immunocytochemistry; inferior alveolar nerve; in situ hybridisation; nerve injury; neuroma; SNS PN3; sodium channel; trigeminal ganglion;

    Abstract : Iatrogenic injuries to branches of the trigeminal nerve are common during surgical procedures in the jaws and teeth, and as the repercussion of facial fractures or certain pathologies. A portion of these patients are left with disturbed sensory functions, and some with unpleasant abnormal sensations, including pain. READ MORE

  2. 2. Tetrodotoxin-resistant sodium channels in neuropathic pain

    Author : Jenny Fjell Hjelmström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : spinal sensory neurons; nociceptor; IB4; tetrodotoxin; sodium channels; SNS PN3; NaN SNS2; gene regulation; NGF; GDNF; in situ hybridization; immunofluorescence; sodium currents; neuropathic pain models; Taiep;

    Abstract : Injury to the peripheral nervous system can cause neuropathic pain. Abnormal sodium channel activity has been implicated as a source of ectopic firing and changes in nociceptive threshold following nerve injury. READ MORE

  3. 3. Neuropeptides, sensory neurons and pain modulation

    Author : Pablo R Brumovsky; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the present thesis work we have analyzed the expression, regulation and function of two neuropeptides: galanin and neuropeptide tyrosine (NPY). Their associated receptors, galanin receptor-1 and -2 (GaIR1, -R2) and NPY Y1- and Y2R, were also studied. READ MORE