Search for dissertations about: "chronic graft-versus-host disease"

Showing result 1 - 5 of 30 swedish dissertations containing the words chronic graft-versus-host disease.

  2. 1. Clinical aspects of chronic graft-versus-host disease

    Author : Gabriel Afram; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic graft-versus-host disease (cGVHD) remains one of the most severe complications after allogeneic hematopoietic stem cell transplantation (HSCT), affecting both the quality of life and mortality of long-term survivors. Its impact on morbidity and mortality varies depending on the severity and number of organs involved, allowing classification into mild, moderate, and severe cGVHD according to the National Institute of Health criteria (NIH). READ MORE

  4. 2. Oral chronic Graft-versus-host disease : clinical and pathological staging

    Author : Victor Tollemar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Allogenic hematopoietic cell transplantation (HCT) is a curative treatment for many patients with immune- hematopoietic disorders, mainly hematopoietic cancers as leukaemia. Chronic Graft-versus-Host Disease (cGVHD) is a major long-term complication, associated with mortality and morbidity following allogenic HCT. READ MORE

  5. 3. Graft-versus-Host Disease: Eosinophils, Chimerism and Clinical Features in Patients Undergoing Allogeneic Hematopoietic Stem Cell or Multivisceral Transplantation

    Author : Julia Cromvik; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; graft-versus-host disease; eosinophilic granulocyte; intestinal transplantation; multivisceral transplantation; chimerism analysis;

    Abstract : Abstract Graft-versus-host disease (GVHD) is a potentially severe complication that may develop after allogeneic hematopoietic stem cell transplantation (HSCT). It can also occur after transplantation with isolated intestinal grafts or after multivisceral transplantation (MVTX). GVHD is difficult to diagnose. READ MORE

  6. 4. Graft-versus-host disease and treatment with mesenchymal stromal cells

    Author : Lena von Bahr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Graft-versus-host disease of both the acute (aGvHD) and chronic (cGvHD) variety remains a major cause of mortality and morbidity after allogeneic hematopoietic stem cell transplantation (HSCT). During the last 15 years, mesenchymal stromal cells (MSC) have been explored as a promising new treatment for aGvHD, but there are many questions to be answered in this young field. READ MORE

  7. 5. Female genital Graft-versus-Host Disease - Diagnosis, Treatment, Incidence, Long-term Prevalence, and Impact on Androgen Hormones and Sexual Function

    Author : Eva Smith Knutsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allogeneic stem cell transplantation; chronic graft-versus-host disease; female genitalia; diagnostic; treatment; androgens in women; glucocorticosteroids; sexual dysfunction;

    Abstract : ABSTRACT BACKGROUND. Chronic graft-versus-host disease (cGvHD) is the major cause of morbidity after allogeneic hematopoietic stem cell transplantation (alloSCT), and contributes to non-relapse mortality. Caused by donor cells, cGvHD is a multi-organ syndrome involving tissue inflammation and fibrosis. AIMS. READ MORE