Search for dissertations about: "chronic itp"

Showing result 1 - 5 of 6 swedish dissertations containing the words chronic itp.

2. 1. On cellular immunology in chronic idiopathic thrombocytopenic purpura (ITP)

   Author : Per-Ola Andersson; Göteborgs universitet; []
   Keywords : chronic ITP; T-cells; TGF-b1; Th3; cell-mediated cytotoxicity; KIR; DNA microarray;

   Abstract : Chronic idiopathic thrombocytopenic purpura (ITP) is an acquired autoimmune disease characterized by a low platelet count and mucocutaneous bleedings. Chronic ITP is considered to be mediated by autoantibodies leading to premature destruction of platelets in the reticuloendothelial system. READ MORE

4. 2. Epidemiological perspective of chronic immune thrombocytopenia

   Author : Charlotta Ekstrand; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : This thesis deals with different aspects of immune thrombocytopenia disease (ITP), what happens before diagnosis, characteristics of patients at treatment start and outcomes potentially related to the disease and treatment, such as thrombosis and cancer. In study one we investigate the risk of infections prior to the diagnosis of ITP. READ MORE

5. 3. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention

   Author : Tobias Svensson; Honar Cherif; Martin Höglund; Jan Sjölin; Christine Wennerås; Uppsala universitet; []
   Keywords : Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

   Abstract : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. READ MORE

6. 4. Idiopathic thrombocytopenic purpura in childhood : clinical features, diagnostics and treatment

   Author : Iris Treutiger; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Idiopathic thrombocytopenic purpura; childhood; treatment; morbidity; outcome; T cell expansion; T cell receptor;

   Abstract : Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by thrombocytopenia, i.e. platelet count (pl.c. READ MORE

7. 5. Studies on antibodies against phospholipids

   Author : Leopold Årfors; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Antiphospholipid syndrome; anticardiolipin antibodies; lupus anticoagulants; platelets; platelet activation; complement activation; endothelial cells; thromboxane; prostacyclin; acetylsalicylic acid.;

   Abstract : The main clinical features of the antiphospholipid syndrome (APLS) are arterial and venous thrombosis, repeated spontaneous abortions and thrombocytopenia. Diagnosed concomitant with an underlying disease the designation is secondary APLS; otherwise primary APLS. READ MORE