Search for dissertations about: "chronic myeloid leukemia cml"

Showing result 21 - 25 of 32 swedish dissertations containing the words chronic myeloid leukemia cml.

  2. 21. The methodology and significance of minimal residual disease detection after allogeneic stem cell transplantation

    Author : Mehmet Uzunel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Minimal Residual Disease; Stem Cell Transplantation; ALL; AML; CML; Relapse;

    Abstract : Allogeneic stem cell transplantation (SCT) is the choice of therapy for leukemia patients who respond poorly to conventional chemotherapy. Despite high remission rates after SCT, relapse of the underlying disease remains one of the most frequent causes of treatment failure. READ MORE

  4. 22. Molecular and functional studies of ABL1 and FGFR1 fusion oncogenes in myeloproliferative neoplasms

    Author : Helena Ågerstam; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The tyrosine kinase encoding genes ABL1 and FGFR1 are involved in fusion genes underlying the myeloproliferative neoplasms chronic myeloid leukemia (CML) and the 8p11-myeloproliferative syndrome (EMS). CML and EMS are both myeloproliferative disorders with an initiating, relatively indolent, chronic phase that after some time progresses into acute myeloid or lymphoid leukemia. READ MORE

  5. 23. In vitro studies on anti-leukemic effects of tetracycline's analogues and cyclophosphamide

    Author : Mona Fares; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Leukemia is a heterogeneous group of hematological malignancies that originate from the bone marrow. Leukemias are classified as acute or chronic. Although acute leukemia affects patients of all ages, acute lymphoid leukemia is predominant in children and young adults while acute myeloid leukemia (AML) is predominant in the elderly. READ MORE

  6. 24. Comorbidity in risk and outcome of hematological malignancies

    Author : Mohammad Mohammadi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hematological malignancies are a group of neoplasms that originate from the bone marrow or lymphatic tissues representing close to 10% of the overall cancer burden in the world. Clinical course, prognosis and survival varies greatly from very aggressive disease requiring intensive systemic chemotherapy-based treatment to indolent forms without need of therapy at diagnosis. READ MORE

  7. 25. Development of Adenoviral Vectors for Studying Hematopoietic Stem Cell Function

    Author : Marcus Järås; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; hTERT; adenovirus; hematopoietic stem cells; Haematology;

    Abstract : Hematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. READ MORE