Search for dissertations about: "circular dichroism"

Showing result 1 - 5 of 90 swedish dissertations containing the words circular dichroism.

  1. 1. Biological and Biophysical Studies on Ruthenium Complexes

    Author : Anna Mårtensson; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metal susceptibility; DNA; antimicrobial; circular dichroism; ruthenium complex; linear dichroism; isothermal titration calorimetry; intercalation;

    Abstract : Small molecules that interact with DNA through intercalation are attractive candidates for treatments against cancer and microbial infections. Octahedral ruthenium(II) polypyridyl complexes, being substitution-inert, readily synthesized and coordinately saturated, has the potential of being developed in to a new family of drugs. READ MORE

  2. 2. Biophysical studies of membrane interacting peptides derived from viral and Prion proteins

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Kamila Oglęcka; Stockholms universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Prion peptides; Doppel peptide; Influenza fusion peptides; peptide-membrane interactions; translocation; linear dichroism; circular dichroism; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : This thesis focuses on peptides derived from the Prion, Doppel and Influenza haemagglutinin proteins in the context of bilayer interactions with model membranes and live cells. The studies involve spectroscopic techniques like fluorescence, fluorescence correlation spectroscopy (FCS), circular and linear dichroism (CD and LD), confocal fluorescence microscopy and NMR. READ MORE

  3. 3. DNA-Complexes with Drugs and Proteins

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Louise Fornander; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Circular Dichroism; Linear Dichroism; Minor groove binder; DNA strand exchange; HsRad51; Isothermal Titration Calorimetry; Hoechst 33258;

    Abstract : DNA is fundamental for all living cells; the DNA holds the genetic code, which is more or less the instruction book for how all cells are built and function. Several diseases are also linked to DNA, emerging either from a mutation in our genome, which could result in a malfunctioning protein, or that the transcription of genes is somehow affected by structural changes in the DNA, induced by mutations or DNA binding molecules. READ MORE

  4. 4. Amyloid Fibril Formation - Dye Detection and Effects of Lipids

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : David Lindberg; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atomic force microscopy; fluorescence; Alzheimer’s disease; YOYO-1; amyloid fibrils; lipids; linear dichroism; FRET; circular dichroism; kinetics; Protein aggregation; insulin; thioflavin-T;

    Abstract : Amyloid fibrils are long fibrillar homopolymers of self-assembled proteins. They can be formed by essentially any polypeptide, but are of particular interest because of their occurrence in several incurable and debilitating human diseases, e.g. Alzheimer’s disease (AD). READ MORE

  5. 5. Long-range intermolecular dispersion forces and circular dichroism spectra from first-principles calculations

    University dissertation from Institutionen för fysik, kemi och biologi

    Author : Auayporn Jiemchooroj; Linköpings universitet.; Linköpings universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; van der Waals forces; dispersion forces; dispersion coefficients; polarizability; electronic circular dichroism; NATURAL SCIENCES Physics; NATURVETENSKAP Fysik;

    Abstract : This work presents first-principles calculations of long-range intermolecular dispersion energies between two atoms or molecules and of electronic circular dichroism spectra of chiral molecules. The former is expressed in terms of the C6 dipole-dipole dispersion coefficients Δε, and the latter is given in terms of the extinction coefficient. READ MORE