Search for dissertations about: "circulating fatty acids"

Showing result 21 - 25 of 45 swedish dissertations containing the words circulating fatty acids.

  1. 21. Genetic and metabolic studies of APOE, PCSK9, TM6SF2 and PNPLA3

    Author : Hovsep Mahdessian; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lipids – including fatty acids (FAs), triglycerides (TGs), cholesterol and cholesterol esters (CEs) – are hydrophobic molecules involved in several important structural and mechanistic processes. Lipids are found in cellular membranes, give posture and stability to the cell, are actively participating in cellular signaling, and act as mediators in several important biological pathways. READ MORE

  2. 22. Protein expression analysis of insulin producing cells exposed to endoplasmic reticulum stress

    Author : Victoria Rosengren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly as a result of the obesity epidemic. T2DM develops in individuals who fails to compensate for increased demand of insulin. READ MORE

  3. 23. Can fish oil in pregnancy and lactation alter maternal and infant immunological responses and prevent allergy in the offspring?

    Author : Catrin Furuhjelm; Karel Duchén; Karin Fälth-Magnusson; Catarina Almqvist Malmros; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Background: A connection has been proposed between the increase of allergic disease and the altered composition of fatty acids in the diet in the westernised world. Less oily fish and more vegetable oil are consumed today compared to 50-100 years ago. READ MORE

  4. 24. The role of galectin-1 in type 2 diabetes. Clinical and experimental studies

    Author : Emanuel Fryk; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-1; type 2 diabetes; human; adipose tissue; metabolism;

    Abstract : Aim: The purpose of this thesis was to identify a new agent in the subcutaneous adipose tissue and assess its clinical potential in the context of type 2 diabetes. Study I: Through a combination of microdialysis and mass-spectrometry, we found increased galectin-1 levels in the subcutaneous adipose tissue in a small experimental study of 15 men with and without type 2 diabetes. READ MORE

  5. 25. Maternal obesity and offspring metabolic outcomes : focus on sex differences

    Author : Christina Savva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is a worldwide health issue affecting all ages and both sexes, and its prevalence is progressively increasing among adults and children. The predisposition to metabolic complications caused by obesity is sex dependent. READ MORE