Search for dissertations about: "clathrin-coated vesicles"

Showing result 1 - 5 of 12 swedish dissertations containing the words clathrin-coated vesicles.

2. 1. From a candidate region to gene characterization : analysis of three new genes with respect to meningioma tumorigenesis

   Author : Myriam Peyrard; Karolinska Institutet; Karolinska Institutet; []
   Keywords : meningioma; central nervous system; monosomy 22; tumor suppressor gene; ADTBI BAM22 gene; clathrin-coated vesicles; adaptin; assembly protein;

   Abstract : Meningioma is a common and usually benign tumor arising from the meninges covering the central nervous system (CNS). The yearly incidence of symptomatic meningiomas is 1.2 cases per 100 000 individuals but autopsy findings reveal an occurrence ten times higher. READ MORE

4. 2. Synaptic vesicle endocytosis studied in a living synapse

   Author : Helge Gad; Karolinska Institutet; Karolinska Institutet; []
   Keywords : synapse; synaptic vesicles; endocytosis; clathrin; calcium; dynamin; endophilin; amphiphysin; synaptojanin; microinjection; electron microscopy;

   Abstract : Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic plasma membrane. The neurotransmitter diffuses to the neighboring neuron and triggers a new electrical signal. READ MORE

5. 3. Molecular mechanisms in synaptic vesicle recycling

   Author : Joel Jakobsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Neurons communicate through specialized contacts called synapses, which consist of pre- and postsynaptic compartments separated by a narrow synaptic cleft. The stimulus- dependent rapid influx of calcium ions into the presynaptic compartment induces fusion of neurotransmitter-filled vesicles with the plasma membrane and release of their content into the synaptic cleft. READ MORE

6. 4. Coordination of endocytosis at the synaptic periactive zone

   Author : Emma Evergren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Synapse; endocytosis; clathrin; dynamin; amphiphysin; synapsin; intersectin; actin cytoskeleton; immunogold electron microscopy.;

   Abstract : Neurons in the central nervous system communicate via specialized junctions called synapses. Neurotransmitter-filled vesicles are clustered at these junctions, where they are released in response to synaptic activity. To sustain reliable neurotransmission the synaptic vesicles are recycled locally. READ MORE

7. 5. Cytoskeletal mechanisms in synaptic vesicle recycling

   Author : Jenny Gustafsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Synapse; actin cytoskeleton; synaptic vesicle; endocytosis;

   Abstract : This thesis explores cytoskeletal mechanisms involved in the recycling of synaptic vesicles. As an initial step it characterizes synapses formed by giant reticulospinal axons in lamprey and defines their use as a model system. The most common type of reticulospinal synapse, "simple synapse", appeared to be most suitable as an experimental model. READ MORE