Search for dissertations about: "claudin"

Showing result 1 - 5 of 16 swedish dissertations containing the word claudin.

  1. 1. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

    Author : Yihong Zhu; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

    Abstract : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. READ MORE

  2. 2. Cell adhesion proteins in different invasive patterns of colon carcinomas : a morphometric and molecular genetic study

    Author : Victoria Hahn-Strömberg; Lennart Franzén; Richard Palmqvist; Örebro universitet; []
    Keywords : AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; colon carcinoma; growth pattern; tight junction; Complexity Index; cell adhesion; E-cadherin; Beta-catenin; Occludin; Claudin.; Medicine; Medicin; Biomedicin; Biomedicine;

    Abstract : Colorectal carcinoma is the second most common type of cancer in both men and women in Sweden. Cancer of the colon and rectum are often considered together and their ten year survival rate is approximately 50 – 60 % depending on sex and location. READ MORE

  3. 3. An integrative strategy for targeted evaluation of biomarker expression in non-small cell lung cancer

    Author : Johanna Mattsson; Patrick Micke; Johan Botling; Fredrik Pontén; Åslaug Helland; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-small cell lung cancer; prognostic biomarkers; predictive biomarkers; immunohistochemistry; gene expression; COX-2; claudin; ALK; Medicinsk vetenskap; Medical Science;

    Abstract : Despite improvements in therapy, the prognosis for non-small cell lung cancer (NSCLC) patients remains poor, and cure is only possible in localized tumors after surgical resection. A new generation of targeted cancer drugs has led to the expectation that lung cancer therapy can be significantly improved, but these drugs are today only an option in a small subset of NSCLC patients, and their effect is temporary. READ MORE

  4. 4. Coeliac Disease in Childhood : On the Intestinal Mucosa and the Use of Oats

    Author : Elisabet Hollén; Karl-Eric Magnusson; Marie-Louise Hammarström; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiaki; havre; avenin; anti-aveninantikroppar; NO; tight junctions; occludin; claudin; Medical microbiology; Medicinsk mikrobiologi;

    Abstract : Celiaki, eller glutenintolerans, är en av våra vanligaste kroniska sjukdomar i barnaåren. Sjukdomen orsakar en kraftig inflammation i tunntarmens slemhinna efter intag av glutenhaltig föda hos personer med ärftlig benägenhet att utveckla celiaki. En frisk tarm är kraftigt veckad för att öka ytan för upptag av näringsämnen. READ MORE

  5. 5. Protein kinase C-dependent regulation of the epithelial barrier

    Author : Anita Sjö; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The intestinal epithelium is essential for the absorption of nutrients and for the defence against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by the intercellular tight junctions. READ MORE