Search for dissertations about: "claudin"

Showing result 11 - 15 of 18 swedish dissertations containing the word claudin.

  2. 11. Intestinal transplantation. Experimental and clinical studies

    Author : Mihai Oltean; Göteborgs universitet; []
    Keywords : Intestinal preservation; Ischemia-reperfusion injury; Tight junction; FK506; Resistin;

    Abstract : Intestinal preservation-reperfusion injury may result in various degrees of mucosal injury. Interestingly, the preservation injury is similar when using the current preservation solutions, which are given as a intravascular flush. An extensive mucosal injury may ultimately preclude the use of organs that require longer preservation time. READ MORE

  4. 12. CD93 in regulation of vascular function and tumour progression

    Author : Kalyani Vemuri; Anna Dimberg; Pipsa Saharinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD93; Tumour angiogenesis; Vascular permeability; Endothelial junctions; Cancer; Glioblastoma; Metastasis;

    Abstract : To achieve successful vascular targeting in cancer, a better understanding of the molecular mechanisms that lead to tumour vascular abnormalities is required.  The transmembrane protein CD93 is highly expressed in the vasculature of several tumours including glioblastoma and has emerged as a potential anti-angiogenic target. READ MORE

  5. 13. Immune response of the small intestinal mucosa in children with celiac disease : impact of two environmental factors, resident microbiota and oats

    Author : Veronika Sjöberg; Marie-Louise Hammarström; Olle Hernell; Katri Kaukinen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; Oats; Microflora; Immune response; immunologi; Immunology;

    Abstract : Celiac disease (CD) is an immune-mediated enteropathy caused by permanent intolerance to dietary gliadin in wheat gluten and related prolamines in barley and rye. The pathogenesis of CD is still unknown and several different environmental factors have been associated with CD, such as dysbiosis of the microflora. READ MORE

  6. 14. In vitro studies on the mechanisms of inhibited thyroidal iodide uptake and destructive thyroiditis as adverse effects of amiodarone and interferon-gamma

    Author : Sofia Tedelind; Göteborgs universitet; []
    Keywords : thyroid; amiodarone; interferon-gamma; iodide transport; tight junction; mitochondria; endocytosis;

    Abstract : The clinical use of the potent anti-arrhythmic drug amiodarone is limited due to adverse effects e.g. in the thyroid comprising both hypo- and hyperthyroidism. Amiodarone-induced thyroid dysfunction can occur in subjects with normal thyroid glands but also in those with an underlying thyroid abnormality resulting in an aggravation of the condition. READ MORE

  7. 15. Intestinal adaption in response to Roux-en-Y gastric bypass surgery

    Author : Erik Elias; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; obesity; bariatric surgery; proteomic analysis; intestinal permeability; calcium; bone mineral density; lipid metabolism;

    Abstract : ABSTRACT Background: Obesity is a condition with increasing prevalence that leads to morbidity, decreased quality of life and reduced life expectancy. The only effective evidence-based treatment is bariatric surgery. READ MORE