Search for dissertations about: "click chemistry"

Showing result 21 - 25 of 43 swedish dissertations containing the words click chemistry.

  2. 21. Modular Enzyme-Responsive Polysaccharide-Based Hydrogels for Biofabrication

    Author : Sajjad Naeimipour; Daniel Aili; Robert Selegård; Alireza Dolatshahi-Pirouz; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 3D cell-culture; Bioprinting; Alginate; Hyaluronan; Cancer model;

    Abstract : Engineered human tissue and disease models can decrease the cost and time of developing new drugs and treatments, facilitate personalized medicine, and eliminate the need for animal models that poorly represent the human body and are ethically problematic. However, the current conventional cell expansion methods using 2D culture flasks cannot enable the development of such complex multi-cellular 3D models. READ MORE

  4. 22. Concatemerization of Synthetic Oligonucleotides, Assembly on Surface and Ligand Interactions

    Author : Lu Sun; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA formation; DNA concatemer; self-assemble; gel electrophoresis; DNA-binding; hybridization; QCM-D;

    Abstract : DNA nanotechnology has become an important research field because of its advantages in high predictability and accuracy of base-paring recognition. DNA concatemer, one of the simplest DNA constructs in shape, have been found as efficient signal amplifiers in several biosensors for different applications. READ MORE

  5. 23. Concatemerization of Synthetic Oligonucleotides

    Author : Lu Sun; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gel electrophoresis; DNA-binding; QCM-D; DNA concatemer; hybridization; DNA formation; self-assembly;

    Abstract : DNA nanotechnology has become an important research field because of its advantages in high predictability and accuracy of base-paring recognition. For example, the DNA concatemer, one of the simplest DNA constructs in shape, has been used to enhance signals in biosensing. READ MORE

  6. 24. Molecular Recognition Materials Synthesized Based on Small molecules, DNA, and Imprinted Polymers for Bioanalytical Applications

    Author : Xiaoting Xue; Tillämpad biokemi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; detection; molecularly imprinted polymers; boronic acid; DNA; dendritic fibrous nanosilica;

    Abstract : The development of sensitive, convenient, and cost-effective methods for detecting disease biomarkers is very important for meeting the growing demand for early clinical diagnosis. Additionally, the detection of disease biomarkers at ultralow concentrations is very important for disease prevention and treatment and posttreatment rehabilitation. READ MORE

  7. 25. Fixation of Functionalized DNA Nanostructures

    Author : Erik Lundberg; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; triplex recognition; dna; self-assembly; gel electrophoresis; nanotechnology; cross-linking; spectroscopy; fixation; fret; click chemistry;

    Abstract : This thesis features results from two different studies on a fully addressable non-repetitive network on the nanometre scale, assembled by synthetic DNA molecules. A bio-inspired molecular approach, based on principles of self-assembly, has brought about a paradigm shift in nanoscience, from a top-down to a bottom-up perspective. READ MORE