Search for dissertations about: "clinical microbiology"

Showing result 6 - 10 of 203 swedish dissertations containing the words clinical microbiology.

  2. 6. Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community

    Author : Micael Widerström; Johan Wiström; Tor Monsen; Anders Sjöstedt; Bo Söderquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; staphylococcus epidermidis; staphylococcus saprophyticus; electrophoresis; gel; pulsed-field; genetic diversity; methicillin-resistance; UTI; drug resistance; multiple; bacterial; epidemiology; molecular; cross infection; molecular sequence data; Medical microbiology; Medicinsk mikrobiologi; Clinical bacteriology; Klinisk bakteriologi; Infectious diseases; Infektionssjukdomar; Clinical Bacteriology; klinisk bakteriologi; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Abstract : Background Coagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). READ MORE

  4. 7. Biological and Pharmacological Factor that Influence the Selection of Antibiotic Resistance

    Author : Ingegerd Gustafsson; Otto Cars; Niels Frimodt-Möller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Human microflora; antibiotic resistance; selection; mutation frequency; biological fitness; pharmacokinetics; pharmacodynamics; β-lactam antibiotics; suboptimal dosing regimen; Mikrobiologi; Microbiology; Mikrobiologi; Klinisk bakteriologi; Clinical Bacteriology;

    Abstract : Antibiotic treatment causes an ecological disturbance on the human microflora. Four commensal bacteria: E. coli, enterococci, a-streptococci and coagulase-negative staphylococci, from patients with extensive, high antibiotic usage were investigated with regard to resistance pattern and mutation frequency. READ MORE

  5. 8. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Author : Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  6. 9. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Author : Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Abstract : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. READ MORE

  7. 10. Responses to External Cues in Oral Bacteria

    Author : Carolina Robertsson; Claes Wickström; Gunnel Svensäter; Julia R Davies; Mattias Collin; Malmö universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral Microbiology; Oral Biofilms; Saliva; Salivary mucin MUC5B; Streptococcus; Actinomyces;

    Abstract : This thesis investigates responses to external cues in oral bacteria on a molecular level. Paper I maps Ser/Thr/Tyr phosphorylated proteins in relation to the general proteome in an oral commensal streptococcus (Streptococcus gordonii DL1). READ MORE