Search for dissertations about: "clinical relevance"

Showing result 1 - 5 of 371 swedish dissertations containing the words clinical relevance.

  1. 1. SCHIZOPHRENIA IN A LONGITUDINAL PERSPECTIVE clinical and neurocognitive aspects

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Jonas Eberhard; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxikologi; farmaci; farmakognosi; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; Folkhälsa; epidemiologi; epidemiology; Public health; psykosomatik; klinisk psykologi; Psykiatri; psychosomatics; clinical psychology; Psychiatry; longitudinal; shared decision making; schizophrenia; cognition; prolactin; tardive dyskinesia; remission; Medicine human and vertebrates ; insight; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Objective: To explore the long-term course and to study factors of potential relevance for the treatment and rehabilitation process of patients with schizophrenia and schizophrenia-like disorders. Specific issues concerned cognitive reduction, tardive dyskinesia (TD), prolactin-induced side effects, remission and lack of insight. READ MORE

  2. 2. Clinical relevance of high-sensitive Troponin T in cardiovascular disease

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Christian Bjurman; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; prognostic score; mortality; heart failure; myocardial infarction; renal dysfunction;

    Abstract : Background and aims: Troponin T (hs-cTnT) is a cardiac damage marker used in the diagnosis of non-ST segment elevation myocardial infarction (NSTEMI) and for prognostic assessment. Clinical decision-making should ideally be based on evidence. READ MORE

  3. 3. Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 Biological and Clinical Aspects

    University dissertation from Uppsala University : Acta Universitatis Upsaliensis

    Author : Abir Salwa Ali; Uppsala universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The aim of this thesis was to investigate biological and clinical aspects of G3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs).In our first study, the expression of the tumor suppressor p53 was investigated. In a cohort of G3 GEP-NENs we found the expression of p53 protein to be present in 39% of 124 cases. READ MORE

  4. 4. Clinical Pharmacogenetics of Olanzapine with Focus on FMO Gene Polymorphisms

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mao Mao Söderberg; Uppsala universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; olanzapine; pharmacogenetics; drug metabolism; schizophrenia; therapeutic drug monitoring; FMO1; FMO3; CYP1A2; UGT1A4; Clinical Pharmacology; Klinisk farmakologi;

    Abstract : Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. READ MORE

  5. 5. The clinical relevance of vertebral fractures and low back pain in elderly men

    University dissertation from Clinical and Molecular Osteoporosis Research Unit, Clinical Sciences, Malmö

    Author : Mehrsa Kherad; Lund University.; Lunds universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The number of vertebral fractures has increased during the last few decades.The increase could at least partly be explained by the increasing proportion of elderly in society since these fractures are more commonly found in elderly than in young individuals. READ MORE