Search for dissertations about: "clinical trial analysis"

Showing result 1 - 5 of 320 swedish dissertations containing the words clinical trial analysis.

  2. 1. Medication reviews by clinical pharmacists in older hospitalised patients : Implementation, performance and effects

    Author : Thomas G. H. Kempen; Ulrika Gillespie; Håkan Melhus; Elisabet I. Nielsen; Derek Stewart; Stephen Byrne; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medication review; medication reconciliation; multi-professional collaboration; hospital medicine; polypharmacy; inappropriate prescribing; drug-related problems; medication-related hospital admissions; pragmatic clinical trial; cluster analysis; randomised controlled trial; qualitative analysis; process evaluation; implementation science; Geriatrics; Geriatrik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Internal Medicine; Internmedicin; Hälso- och sjukvårdsforskning; Health Care Research;

    Abstract : Background Inappropriate use of medications is a leading cause of avoidable harm in health care. Medication reviews by clinical pharmacists improve medication use, but evidence on hard clinical outcomes in older hospitalised patients is scarce and implementation in practice is challenging. READ MORE

  4. 2. Depression in teenagers and young adults : foundational studies of the new treatment paradigm TARA: Training for Awareness, Resilience, and Action

    Author : Erik Ekbäck; Eva Henje Blom; Ida Blomqvist; Jenny Molin; Inga Dennhag; Thorbjörn Lundberg; Elizabeth McCauley; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; adolescents; young adults; medical students; mental health; anxiety; psychological stress; qualitative research; randomization; yoga; mindfulness; psychotherapy; antidepressant drugs; biomarkers; clinical trial; feasibility studies; online intervention; reliability; validity; confirmatory factor analysis; measurement invariance; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Abstract : Introduction: Depression in adolescents and young adults is an increasing global health concern and available treatments are not convincingly effective. It is therefore important to develop and test novel treatments to improve treatment outcomes. READ MORE

  5. 3. IgA Nephropathy – Mucosal Immunity and Treatment Options

    Author : Hilde Kloster Smerud; Bengt Fellström; Gudjon Kristjansson; Roger Hällgren; Johan W. de Fijter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA nephropathy; mucosal immunity; gastrointestinal sensitivity; food allergens; pharmacological treatment; budesonide; statin; clinical trial; renal transplantation; recurrence; Internal Medicine; Internmedicin;

    Abstract : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. READ MORE

  6. 4. No touch vein harvesting technique for coronary artery by-pass surgery : impact on patency rate, development of atheroscleosis, left ventricular function and clinical outcome during 16 years follow-up

    Author : Benny Johansson; Eva Swahn; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; coronary artery disease; coronary artery bypass grafting; vein grafts; no touch vein harvesting technique; intravascular ultrasound; echocardiography; clinical outcome; revascularization; outcome analysis; angina pectoris; myocardial infarction; mortality; randomized trial; Surgery; Kirurgi;

    Abstract : This thesis was based on a prospective randomized trial which was started in 1993 to compare the no touch (NT) with the conventional (C) technique of saphenous vein harvesting for CABG.In paper I, was demonstrated superior patency for the NT grafts at short-term (1.5 years; 95,6% vs 89%; p < 0,05) and long-term follow-up (8. READ MORE

  7. 5. Effect of antihypertensive treatment at different blood pressure levels

    Author : Mattias Brunström; Bo Carlberg; Mats Eliasson; Sverre Kjeldsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood pressure; hypertension; antihypertensive treatment; cardiovascular disease; randomized controlled trial; systematic review; meta-analysis; standardization;

    Abstract : BackgroundHigh blood pressure is associated with an increased risk of cardiovascular disease and premature death. The shape of association between blood pressure and the risk of cardiovascular events is debated. Some researchers suggest that the association is linear or log-linear, whereas others suggest it is J-shaped. READ MORE