Search for dissertations about: "clinical trial regulation"
Showing result 1 - 5 of 34 swedish dissertations containing the words clinical trial regulation.
-
1. On the Optimisation and Regulation of Clinical Trials
Abstract : The basic premise of this thesis is that Bayesian Decision Theory (BDT) can and should be used to solve clinical trial design problems. While the flexibility of the framework allows for accommodating a great variety of situations, it also requires an explicit consideration of the gains and costs associated with the trial. READ MORE
-
2. Optimisation of Clinical Trials using Bayesian Decision Theory
Abstract : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. READ MORE
-
3. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer
Abstract : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. READ MORE
-
4. Sentinel Node Biopsy in Breast Cancer : Clinical and Immunological Aspects
Abstract : The most important prognostic factor in breast cancer is the axillary lymph node status. The sentinel node biopsy (SNB) is reported to stage the axilla with an accuracy > 95 % in early breast cancer. Tumour-related perturbation of T-cell function has been observed in patients with malignancies, including breast cancer. READ MORE
-
5. Targeting the role of statins in breast cancer – through translationally edged clinical trials
Abstract : AbstractBreast cancer incidence is increasing, and despite major progress in the treatment, breast cancer is still the leading cause of death from cancer among women. Thus, there is a constant need for new treatment options. READ MORE