Search for dissertations about: "clinical trials participation"

Showing result 1 - 5 of 22 swedish dissertations containing the words clinical trials participation.

2. 1. Patients in Clinical Cancer Trials : Understanding, Motivation and Hope

   Author : Tove Godskesen; Ulrik Kihlbom; Peter Nygren; Karin Nordin; Peter Strang; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; adults; clinical trials; phase 1 trials; phase 3 trials; patient information; patient education; informed consent; hope;

   Abstract : The overall aim of this thesis was to study participants' understanding of clinical cancer trials, and their motivation for participation. Of particular interest was the question of whether the patients hoped for a cure resulting from the trial. READ MORE

4. 2. Aural rehabilitation programs for hearing aid users : Evaluating and clinically applying educational programs, supported via telephone and/or the internet and professionally guided by an audiologist

   Author : Milijana Malmberg; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aural rehabilitation; Hearing loss; Counselling; Hearing aids; Internet interventions; Randomized controlled trials; Clinical practice; Patient participation;

   Abstract : Many hearing aid users experience substantial communication difficulties that may affect their participation in daily life situations negatively. This experience can be addressed using follow-up rehabilitation programs, yet the overall availability of such programs in general clinical practice (GCP) is low. READ MORE

5. 3. Perspectives on participation in dementia prevention clinical trials

   Author : Ulrika Akenine; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Dementia is an enormous global health challenge with a rapid increase in the number of people affected. There is an urgent need for research to find effective treatments and preventive strategies. Dementia prevention research is undergoing rapid development with novel approaches and techniques used. READ MORE

6. 4. Parkinson's Disease with Device, Diary, or in Disguise. Dyskinesia reduction, motor state evaluation, and workforce participation among persons with Parkinson's disease

   Author : Jonathan Timpka; Lund Neurologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; Parkinson disease; Levodopa infusion; Motor fluctuations; Dyskinesia; Workforce participation; Work ability; Sickness absence; Employment; Patient reported outcome;

   Abstract : INTRODUCTION: In the wait for disease-modifying treatment for Parkinson’s disease (PD), efforts towards improved symptom control and reduced negative effects of PD can result in meaningful change patients. The general efficacy of levodopa-carbidopa intestinal gel (LCIG) in advanced PD has been established, but its effects on dyskinesia need more investigation. READ MORE

7. 5. Improved Methods for Pharmacometric Model-Based Decision-Making in Clinical Drug Development

   Author : Anne-Gaëlle Dosne; Mats O. Karlsson; Rik Schoemaker; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; nonlinear mixed-effects models; confirmatory trials; residual error modeling; parameter uncertainty; sampling importance resampling; model-averaging; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Pharmacometric model-based analysis using nonlinear mixed-effects models (NLMEM) has to date mainly been applied to learning activities in drug development. However, such analyses can also serve as the primary analysis in confirmatory studies, which is expected to bring higher power than traditional analysis methods, among other advantages. READ MORE