Search for dissertations about: "clonal B cells"
Showing result 1 - 5 of 56 swedish dissertations containing the words clonal B cells.
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1. Switching ON Fetal B Lymphopoiesis
Abstract : B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell response. READ MORE
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2. Regulation of gut IgA induction by helper T cells
Abstract : The gut is the largest lymphoid organ in the body. Due to intense and constant exposure to the outside world, it also functions as the most important portal of entry for many pathogens. READ MORE
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3. Murine B lymphocyte growth regulation : a study of host defence factors and their mimicry by Mycoplasma arginini
Abstract : Immune responses are the result of extended clonal growth and maturation of specific precursors preexisting in low frequencies. Clonal expansion is partly controlled by soluble factors, thus, their identification is essential for the understanding of the immune response regulation. READ MORE
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4. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells
Abstract : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. READ MORE
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5. Identification and Characterization of Stem Cells in Preleukemia and Leukemia
Abstract : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. READ MORE