Search for dissertations about: "clone diversity"

Showing result 16 - 18 of 18 swedish dissertations containing the words clone diversity.

  2. 16. Application of Genomic and Expression Arrays for Identification of new Cancer Genes

    Author : Helena Nord; Teresita Díaz de Ståhl; Jan Dumanski; Susan Pfeifer; Blomquist Erik; Segersten Ulrika; David Gisselsson Nord; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Array-CGH; Expression array; Copy number variation; Glioblastoma; Medulloblastoma; Bladder carcinoma; Oncogenes; Tumor suppressor genes; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Medical genetics; Medicinsk genetik; Tumour biology; Tumörbiologi; Genetics; Genetik; Medical Genetics; Medicinsk genetik;

    Abstract : Copy number variation (CNV) comprises a recently discovered kind of variation involving deletion and duplication of DNA segments of variable size, ranging from a few hundred basepairs to several million. By altering gene dosage levels or disrupting proximal or distant regulatory elements CNVs create human diversity. READ MORE

  4. 17. Characteristics of EBV-infected B cell lines and B-CLL clones which determine their interaction with lymphocytes

    Author : Javier Federico Avila-Carino; Karolinska Institutet; Karolinska Institutet; []
    Keywords : EBV; Burkitt Iymphoma; CLL; MLC; antiviral response phenotype; cytokines.;

    Abstract : The results concerning T Iymphocyte mediated recognition of Epstein-Barr virus (EBV) carrying Burkitt Iymphoma (BL) cell lines and EBV-infected chronic Iymphocytic leukemia (CLL) B cells contribute to the understanding of the generally harmless host-EBV interaction and may be extrapolated to the fate of normal B cells after EBV infection. The phenotype of EBV negative BL lines resembles resting B cells. READ MORE

  5. 18. Novel diagnostic methods for rapid characterization of extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae

    Author : Muhammad Humaun Kabir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Klebsiella pneumoniae and Escherichia coli are two of the most clinically important pathogens of the family Enterobacteriaceae. Both can cause severe infections includ-ing urinary tract infections (UTI), bloodstream infections (BSI) and pneumonia. Both are also involved in dissemination of antibiotic resistance. READ MORE