Search for dissertations about: "clusters cancer"

Showing result 1 - 5 of 61 swedish dissertations containing the words clusters cancer.

  2. 1. Vascular targeting for enhanced cancer immunotherapy

    Author : Maria Georganaki; Anna Dimberg; Sara Mangsbo; Lena Claesson-Welsh; Wolf Hervé Fridman; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; tumor vasculature; endothelial activation; IDO1; ELTD1; tertiary lymphoid organ; Biologi; Biology;

    Abstract : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. READ MORE

  4. 2. Image analysis of prostate cancer tissue biomarkers

    Author : Giuseppe Lippolis; Malmö Urologisk cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; image analysis; Time Resolved Fluorescence; automated Gleason; PSA; AR; fusion gene; TMAs;

    Abstract : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. READ MORE

  5. 3. Molecular studies of endocrine tumors : Insights from genetics and epigenetics

    Author : Samuel Backman; Per Hellman; Peter Stålberg; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Carcinoid; Pheochromocytoma; Aldosterone; Cancer; MEN1; Multiple endocrine neoplasia; Medicinsk vetenskap; Medical Science;

    Abstract : Endocrine tumors may be benign or malignant and may occur in any of the hormone producing tissues. They share several biological characteristics, including a low mutation-burden, and may co-occur in several hereditary tumor syndromes. The aim of this thesis was to identify genetic and epigenetic aberrations in endocrine tumors. READ MORE

  6. 4. Stem and progenitor cells in brain ad breast malignancies

    Author : Gabriella Honeth; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural progenitor cells; glioma; migration; chemokines; cancer stem cells; breast cancer; CD44; CD24;

    Abstract : Stem cells have qualities that clearly distinguish them from all other cells. Capabilities like self-renewal, differentiation and migration make them truly powerful. This thesis deals with different aspects of stem/progenitor cells in relation to cancer. READ MORE

  7. 5. From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

    Author : Atena Malakpour Permlid; NanoLund: Center for Nanoscience; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D tumour models; scaffold-based cultures; cancer cells; electrospun scaffolds; extracellular matrix; tumour microenvironment; high-throughput screening; animal-free; donor herd horse serum; fibroblasts;

    Abstract : Cancer is the second leading cause of death among both men and women worldwide. During therecent years, three-dimensional (3D) tumour models have gained increasing interest as a pre-clinicalplatform for screening of compounds for potential use in cancer therapy. READ MORE