Search for dissertations about: "cns tumor"

Showing result 1 - 5 of 42 swedish dissertations containing the words cns tumor.

  2. 1. Astrocytes, reactive gliosis and CNS regeneration

    Author : Ulrika Wilhelmsson; Göteborgs universitet; []
    Keywords : CNS regeneration; astrocytes; reactive gliosis; intermediate filaments;

    Abstract : The regenerative capacity in the adult central nervous system (CNS) is very limited, and the glial cells have been implicated in the inhibition of CNS regeneration. In essentially all CNS pathologies, astrocytes are activated and this process is known as reactive gliosis. READ MORE

  4. 2. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Author : Malin Blomstrand; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Abstract : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. READ MORE

  5. 3. Adaptation to microenvironmental stress in glioblastoma. Mechanistic studies and potential targets

    Author : Myriam Cerezo-Magaña; Tumörmikromiljö; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glioblastoma; Tumor microenvironment; EVs; Proteoglycans; Tumor Surfaceome;

    Abstract : Although the overall mortality in cancer is steadily decreasing, major groups of patients still respond poorly to available treatments. The key clinical challenge addressed in the present thesis work relates to the inherent adaptive capacity of glioblastoma (GBM) tumors, resulting in treatment resistance and dismal prognosis. READ MORE

  6. 4. Brain tumors in children - National population-based studies on classification, diagnostics and long-term follow-up

    Author : Elizabeth Schepke; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric CNS tumors; population-based; DNA methylation; profiling; CNS-PNET; re-evaluation; incidence rate; long-term outcome; classification; Pediatric CNS tumors; Population-based; DNA methylation; Profiling; CNS-PNET; Re-evaluation; Incidence rate; Long-term outcome; Classification;

    Abstract : Although the prognosis for pediatric tumors of the central nervous system (CNS) has improved over time it is urgent to reduce mortality and improve long-term quality of life for survivors. With this aim, the first step is to identify the correct diagnosis in order to choose the right therapy and avoid unnecessary treatment. READ MORE

  7. 5. Nestin regulation in the embryonic and adult CNS

    Author : Carina Lothian; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The developing mammalian central nervous system (CNS), i.e. the brain and spinal cord, is generated from neuroectodermal stem/progenitor cells lining the neural tube. The CNS stem/progenitor cells proliferate and migrate to give rise to the three principal cell types in the developing CNS: neurons, astrocytes and oligodendrocytes. READ MORE