Search for dissertations about: "cns tumors"

Showing result 1 - 5 of 30 swedish dissertations containing the words cns tumors.

  2. 1. Brain tumors in children - National population-based studies on classification, diagnostics and long-term follow-up

    Author : Elizabeth Schepke; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric CNS tumors; population-based; DNA methylation; profiling; CNS-PNET; re-evaluation; incidence rate; long-term outcome; classification; Pediatric CNS tumors; Population-based; DNA methylation; Profiling; CNS-PNET; Re-evaluation; Incidence rate; Long-term outcome; Classification;

    Abstract : Although the prognosis for pediatric tumors of the central nervous system (CNS) has improved over time it is urgent to reduce mortality and improve long-term quality of life for survivors. With this aim, the first step is to identify the correct diagnosis in order to choose the right therapy and avoid unnecessary treatment. READ MORE

  4. 2. DNA methylation profiling of CNS tumors; implications for clinical diagnostics

    Author : Sandra Ferreyra Vega; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Central nervous system tumors; DNA methylation; clinical diagnostics; diffuse gliomas; meningiomas; heterogeneity;

    Abstract : Diffuse gliomas and meningiomas are the most common primary tumors of the central nervous system (CNS) in adults and these tumors cause significant morbidity and mortality worldwide. Deregulation of the epigenetic mechanisms, e.g. READ MORE

  5. 3. Roles of PDGF for Neural Stem Cells

    Author : Mia Enarsson; Karin Nilsson; Bengt Westermark; Peter Eriksson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; CNS; stem cells; neuron; PDGF; proliferation; differentiation; ERK; microarray; transgenic mouse; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : Stem cells are endowed with unique qualities: they can both self-renew and give rise to new mature cell types. Central nervous system (CNS) stem cells can give rise to neurons and glia. READ MORE

  6. 4. HCMV-induced epigenetic alterations : a novel pathway to CNS tumors?

    Author : Atosa Estekizadeh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aberrant DNA hypermethylation at CpG islands is a well-established phenomenon involved in transcriptional silencing of tumor suppressor genes. CpG island hypomethylation-mediated reactivation of oncogenes is also documented in several cancer types. READ MORE

  7. 5. Molecular Genetic Alterations In Endometrial And Ovarian Cancers

    Author : Anjila Koul; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; KRAS; PTEN; TP53; Overexpression; Mutation; Microsatellite instability; Complex atypical hyperplasia; Endometrial cancer; Ovarian cancer; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; CNS metastasis; Cytogenetic analysis; BRCA2; BRCA1; B-catenin; CDKN2A;

    Abstract : Endometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. READ MORE