Search for dissertations about: "coexpression"

Showing result 1 - 5 of 26 swedish dissertations containing the word coexpression.

  2. 1. N-Sulfation and Polymerization in Heparan Sulfate Biosynthesis

    Author : Jenny Presto; Lena Kjellén; Gunnar Pejler; Anders Malmström; Uppsala universitet; []
    Keywords : Cell and molecular biology; Heparan sulfate; N-deacetylase N-sulfotransferase; NDST; EXT1; EXT2; Biosynthesis; Cell- och molekylärbiologi;

    Abstract : Heparan sulfate (HS) is a glycosaminoglycan present in all cell types covalently attached to core proteins forming proteoglycans. HS interacts with different proteins and thereby affects a variety of processes. READ MORE

  4. 2. Novel findings on cellular trafficking and targeting for granule storage of neutrophil elastase, a multifunctional effector molecule of innate immunity

    Author : Linda Källquist; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic cell; CD63; neutrophil elastase; targeting; trafficking; intracellular sorting; neutrophil; azurophil granule;

    Abstract : Neutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. READ MORE

  5. 3. The architecture of the aging brain : functional reorganization, structural changes, and the role of dopamine receptors

    Author : Robin Pedersen; Alireza Salami; Anna Rieckmann; Anders Wåhlin; Lars Nyberg; Roser Sala-Llonch; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain architecture; functional connectivity; dopamine; aging; cognition; memory; functional magnetic resonance imaging; positron emission tomography; graph theory; Laplacian eigenmapping; gradient;

    Abstract : Aging is associated with reorganization of functional brain architecture, potentially leading tocognitive decline in older age. However, the mechanisms responsible for alterations in functionalbrain architecture remain poorly understood. READ MORE

  6. 4. Meiotic chromosome segregation : molecular analysis of the synaptonemal complex

    Author : Li Yuan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Meiosis is a special type of cell division that produces haploid gametes from diploid parental cells. As such, meiosis stands at the gateway to sexual reproduction in most eukaryotic organisms. During meiosis, a complex, but tightly coordinated series of events occur. Homologous chromosomes come together and pair along their entire length. READ MORE

  7. 5. Regulation of Apoptosis in Hematopoietic Progenitor Cells: Involvement of Different Signaling Pathways

    Author : Maria Kraft; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokines; apoptosis; cell cycle; c-Kit; Flt3; Flt3-ITD; Akt; Bcl-2; FoxO3; mouse; hematopoiesis; progenitor;

    Abstract : Proliferation, differentiation, and survival of hematopoietic stem cells and multipotent progenitor cells are regulated by cytokines and cell-cell interactions. Kit ligand (KL) and Flt3 ligand (FL) have pleiotropic effects, promotes survival, but are nonredundant. READ MORE