Search for dissertations about: "cognitive changes in parkinson disease"

Found 4 swedish dissertations containing the words cognitive changes in parkinson disease.

  2. 1. Characterisation of inputs and outputs of striatal medium spiny neurons in health and disease

    Author : Marko Filipović; Jeanette Hellgren Kotaleski; Arvind Kumar; Gilad Silberberg; Ad Aertsen; Andrew Sharott; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; basal ganglia; striatum; medium spiny neurons; subthalamic nucleus; globus pallidus; Parkinson s disease; in vivo; oscillations; spectral analysis; response variability; networks; simulations; modelling; Numerical Analysis; Numerisk analys; Computer Science; Datalogi; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Abstract : Striatal medium spiny neurons (MSNs) play a crucial role in various motor and cognitive functions. They are separated into those belonging to the direct pathway (dMSNs) and the indirect pathway (iMSNs) of the basal ganglia, depending on whether they express D1 or D2 type dopamine receptors, respectively. READ MORE

  4. 2. Intrinsic brain activity in health and disease

    Author : Pär Flodin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main part of the brain’s energy need is to support housekeeping functions and internal information processing, regardless of external tasks. Cognitive brain imaging, aimed at relating mental phenomena to neurophysiological processes, has conventionally investigated the brain activity induced by external stimuli. READ MORE

  5. 3. Cognitive effects of deep brain stimulation : focus on caudal zona incerta for essential tremor and Parkinson´s disease, and on bed nucleus of stria terminalis for obsessive compulsive disorder

    Author : Johanna Philipson; Patric Blomstedt; Marjan Jahanshahi; Marwan Hariz; Jean-Luc Houéto; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep brain stimulation. Neuropsychology. Cognition. Parkinson’s disease. Essential tremor. Obsessive-compulsive disorder. Caudal zona incerta. Bed nucleus of stria terminalis. Functional MRI.; Neurology; neurologi;

    Abstract : Preserved cognition is an important determinant for perceived Quality of Life (QoL) and has been found to be essential in order to translate improvements in primary symptoms following Deep Brain Stimulation (DBS) into activities of daily living that drive QoL. Therefore, it is important to evaluate not only the clinical improvement, but also the cognitive impact of DBS. READ MORE

  6. 4. Balance and gait in Parkinson’s disease : from perceptions to performance

    Author : Hanna Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis was to explore perceptions and performance of balance and gait in people with Parkinson’s disease (PwPD), and to evaluate both the current evidence for exercise-induced neuroplasticity and the feasibility of investigating exercise-induced neuroplastic changes among PwPD. This thesis includes four papers of different designs; a qualitative interview study (paper I), a systematic review and meta-analysis (paper II), a pilot RCT (paper III) and a crosssectional study (paper IV). READ MORE