Search for dissertations about: "colectomy"

Showing result 16 - 20 of 22 swedish dissertations containing the word colectomy.

  1. 16. Studies on familial adenomatous polyposis

    Author : Jan Björk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Familial adenomatous polyposis (FAP) is a hereditary disorder caused by mutations in the adenomatous polyposis coli (APC) gene, which leads to adenoma formation and subsequently to cancer, predominantly in the colon and the rectum but also in the duodenum. The cancer morbidity and mortality can be decreased by presymtomatic screening and surgical treatment. READ MORE

  2. 17. Glucocorticosteroid therapy and steroid resistance in inflammatory bowel disease

    Author : Lars Flood; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ulcerative colitis; Crohn s disease; Steroid resistance; Glucocorticoid receptor; Nuclear Factor kappaB; Activator Protein 1; Adrenocorticotropin stimulation test; Metallothionein; Rofleponide;

    Abstract : Ulcerative colitis (UC) and Crohn's disease (CD) are diseases of unknown aetiology often referred to as inflammatory bowel diseases (IBD). Glucocorticosteroids (GCS) have been used since the 1950's to treat acute attacks of these diseases. READ MORE

  3. 18. Ulcerative colitis and cancer with special reference to the increased colorectal cancer risk

    Author : Per Karlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ulcerative colitis; cancer; inflammatory bowel disease; colorectal cancer; colonoscopic surveillance; epidemiology; flow cytometry DNA; Sialyl-Tn antigen; primary sclerosing cholangitis; hepatobiliary tract; case-control studies;

    Abstract : The association between ulcerative colitis (UC) and cancer in a defined geographical region in Sweden was analyzed. UC patients have an increased overall risk of cancer of 40%, mainly due not only to the well-known increased risk of colorectal cancer (CRC) but also to the risk of hepatobiliary cancer associated with primary sclerosing cholangitis (PSC). READ MORE

  4. 19. Malignant transformation of the colorectal mucosa in inflammatory bowel disease

    Author : Urban Sjöqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Inflammatory bowel disease; ulcerative colitis; colorectal carcinoma; DNA-FCM; aneuploidy; dysplasia; Crohn s disease.;

    Abstract : Ulcerative colitis (UC) and Crohn's disease (CD) are disorders of unknown etiology, often referred to as inflammatory bowel diseases (IBD). The increased risk of colorectal cancer (CRC) in patients with longstanding, extensive colonic IBD is an important clinical problem. READ MORE

  5. 20. Surgery and stomas in Crohn's disease

    Author : Thordis Disa Kalman; Pär Myrelid; Johan D Söderholm; Bjørn Moum; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : This study investigates the evolution of abdominal surgery in treatment of Crohn´s disease (CD) in the era of immunomodulatory drugs and biologicals. It concerns risk of abdominal surgery overall and sub-categories of abdominal surgery, risk of repeat surgery and factors that affect this risk, and risk of getting a stoma. READ MORE