Search for dissertations about: "colistin resistance"

Showing result 11 - 15 of 21 swedish dissertations containing the words colistin resistance.

  2. 11. Dynamics and Mechanisms of Adaptive Evolution in Bacteria

    Author : Song Sun; Dan Andersson; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; adaptive evolution; mutation; genome rearrangements; antibiotic resistance; gene amplification; genome reduction; directed evolution; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE

  4. 12. Quantifying effects of antimicrobial drug combinations by modelling and simulation

    Author : Chenyan Zhao; Lena Friberg; Elisabet I. Nielsen; Shampa Das; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics and pharmacodynamics; modelling and simulation; antibiotic combination; model-based translation; antibiotic resistance; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. READ MORE

  5. 13. Klebsiella pneumoniae and Escherichia coli : multidrug-resistance and different aspects of invasive infections

    Author : Malin Vading; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Klebsiella pneumoniae and Escherichia coli are pathogens belonging to the Enterobacteriaceae family. They can cause infections ranging from uncomplicated urinary tract infection to severe bloodstream infection (BSI). READ MORE

  6. 14. Molecular Epidemiology and Mechanisms of Antibiotic Resistance in Clinical Isolates of Pseudomonas aeruginosa from Qatar

    Author : Mazen Sid Ahmed; Jana Jass; Emad Ibrahim; Ali Sultan; Bo Söderquist; Christian Giske; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibiotics; C T; CZA; MDR; Pseudomonas aeruginosa; ST235; VEB; VIM;

    Abstract : Inappropriate and excessive use of antibiotics promotes antimicrobial resistance (AMR), particularly in Gram-negative bacteria (GNB). There is a noticeable increase in nosocomial infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa, which is associated with significant morbidity, mortality, and an increase in cost management. READ MORE

  7. 15. Multidrug-resistant Enterobacterales in Oman : molecular epidemiology and therapeutic insights

    Author : Hissa M Al-Farsi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The spread of antibiotic resistance is a concerning issue causing limited treatment options for bacterial infections, particularly with Gram-negative bacteria. Surveillance and epidemiological studies help to determine the magnitude of the problem as well as to establish early measures to slow down the spread of resistance and consequently increase antibiotic lifespan. READ MORE