Search for dissertations about: "collagen synthesis"

Showing result 21 - 25 of 61 swedish dissertations containing the words collagen synthesis.

  2. 21. Immune mechanisms behind plaque vulnerability : experimental and clinical studies

    Author : Olga Ovchinnikova; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Physical disruption of atherosclerotic plaques causes many acute thrombotic complications such as myocardial infarction and stroke. The resistance of the atherosclerotic plaque to disruption depends in part on the integrity of its fibrous cap, which prevents contact between the highly thrombogenic lipid core and the circulating blood. READ MORE

  4. 22. Regulation of hyaluronan biosynthesis : Expression in vitro and importance for tumor progression

    Author : Annica Jacobson; Anders Hjerpe; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Hyaluronan, a component of the extracellular matrix, is synthesized by either of three hyaluronan-synthesizing enzymes termed Has1, Has2 and Has3. The expression level of each Has gene varies between cell types of mesenchymal origin and is differentially regulated in response to external stimuli. READ MORE

  5. 23. Intra- and Extracellular Modulation of Integrin-directed Connective Tissue Cell Contraction

    Author : Tijs van Wieringen; Kristofer Rubin; Anders Arner; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Interstitial fluid pressure; PDGF-BB; bacterial proteins; αVβ3 integrin; cytoskeleton; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : All blood vessels in the microvasculature are embedded in loose connective tissue, which regulates the transport of fluid to and from tissues. The intersti-tial fluid pressure (IFP) is one of the forces that control this transport. READ MORE

  6. 24. Biomarkers of fibrosis in heart failure and relations to left ventricular size, function and outcome

    Author : Johan Löfsjögård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Heart failure (HF) is a syndrome with impaired quality of life and higher mortality than most forms of cancer. The excessive accumulation of collagen in the myocardial extracellular matrix is called myocardial fibrosis, which is a reaction to myocardial stress, myocardial injury and a part of the remodeling process that alters the shape, size, and function of the heart. READ MORE

  7. 25. The Biological Role of the Female Sex Hormone Estrogen in the Periodontium

    Author : Daniel Jönsson; Malmö högskola; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontal ligament cells; Estrogen receptor;

    Abstract : Introduktion: Flera studier har påpekat att det kan finnas ett samband mellan förändringar i nivån av kvinnligt könshormon och förvärrad tandlossning. Hur östrogen påverkar tandfästet är inte kartlagt. Det finns två östrogenreceptorer (ER), ERα och ERβ och betydelsen av de båda receptorerna är inte kartlagda. READ MORE