Search for dissertations about: "collagen synthesis"

Showing result 31 - 35 of 62 swedish dissertations containing the words collagen synthesis.

  2. 31. Studies of Stroma Formation and Regulation in Human Pathological Conditions and in Experimental in vivo Models

    Author : Alejandro Rodriguez; Christian Sundberg; Kristian Pietras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibrosis; Tumor Stroma; Myofibroblast; Pericyte; Angiogenesis; Inflammation; adenovirus; Tumour biology; Tumörbiologi; Molecular medicine; Molekylär medicin; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Fibrosis is a sequel of chronic inflammation and is defined as an excessive deposition of collagen that ultimately leads to organ dysfunction. To date there are no effective treatments for fibrosis. The main cell type involved in collagen deposition and organization is the myofibroblast. READ MORE

  4. 32. The role of MBOAT7 on fatty liver disease

    Author : Andrea Caddeo; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver disease; medicine; Genetics; NAFLD;

    Abstract : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. READ MORE

  5. 33. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation

    Author : Laura Varas; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Medicine human and vertebrates ; Medicin människa och djur ; mesenchymal stem cell; Biomedical sciences; tumor growth inhibition; FGF2; cartilage; integrin alpha11beta1; integrin alpha10beta1;

    Abstract : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. READ MORE

  6. 34. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

    Author : Kenneth B. Jonsson; Uppsala universitet; []
    Keywords : Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. READ MORE

  7. 35. Biosynthesis of decorin and glypican glycosaminoglycan chains

    Author : Mats Jönsson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolism; Biochemistry; phosphorylation; biosynthesis; glycosaminoglycan; decorin; glypican; Biokemi; metabolism;

    Abstract : Proteoglycans consist of core proteins substituted with glycosaminoglycan chains. The galactosaminoglycans (GlcUA/IdoUA-GalNAc) and the glucosaminoglycans (GlcUA/IdoUA-GlcNAc) are both initiated on the same tetrasaccharide linkage region GlcUA-Gal-Gal-Xyl-protein. READ MORE