Search for dissertations about: "collagen-induced arthritis"

Showing result 1 - 5 of 65 swedish dissertations containing the words collagen-induced arthritis.

  1. 1. Collagen induced arthritis : pathogenetic mechanisms and relevance for rheumatoid arthritis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Rikard Holmdahl; Uppsala universitet.; [1985]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  2. 2. Immunomodulation of collagen-induced arthritis

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Lars Mattsson; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; arthritis; collagen type II; immunomodulation; vitamin D; parasite;

    Abstract : Collagen-induced arthritis (CIA) is an experimental autoimmune disease sharing many features with human rheumatoid arthritis (RA). CIA development is dependent on T- cells but anti-collagen type II (anti-CII) antibody production by B-cells is also important. READ MORE

  3. 3. Tolerance Mechanisms in Collagen-Induced Arthritis an Animal Model of Rheumatoid Arthritis

    University dissertation from Lund University, Faculty of Medicine

    Author : Alexandra Treschow; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Tolerance; Regulation; IFN-beta; Macrophages; Immunology; serology; transplantation; Immunologi; serologi; Arthritis; Collage; rheumatology locomotion; muscle system; Skelett; muskelsystem; reumatologi;

    Abstract : Collagen-induced arthritis (CIA) is one of the most commonly used animal models for Rheumatoid arthritis (RA). CIA is induced in susceptible mouse strains after immunization with heterologous type II collagen (CII). In mice of the H-2q haplotype rat CII (rCII) is used whereas in mice of the H-2r haplotype bovine CII is utilized. READ MORE

  4. 4. The MHC-glycopeptide-T cell interaction in collagen induced arthritis a study using glycopeptides, isosteres and statistical molecular design in a mouse model for rheumatoid arthritis

    University dissertation from Umeå : Kemi

    Author : Lotta Holm; Umeå universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rheumatoid arthritis; collagen; T-cell; class II MHC; solid phase peptide synthesis; glycopeptide; peptide isostere; PCA; statistical molecular design; PLS; QSAR; sequence binding motif; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 1% of the population in the western world. It is characterised by a tissue specific attack of cartilage in peripheral joints. Collagen induced arthritis (CIA) is one of the most commonly used animal models for (RA), with similar symptoms and histopathology. READ MORE

  5. 5. Modulation of immune responses in murine collagen induced arthritis

    University dissertation from Göteborg : University of Gothenburg

    Author : Fredrik Bäckström; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Experimental arthritis; type II collagen; immunomodulation; oral tolerance;

    Abstract : Murine collagen-induced arthritis (CIA) is the most common model for studying human rheumatoid arthritis (RA). Autologous or heterologous type II collagen (CII) emulsified in Freund´s complete adjuvant induces arthritis in susceptible mice, which is histopathologically similar to RA. READ MORE