Search for dissertations about: "collagen-induced arthritis"

Showing result 11 - 15 of 71 swedish dissertations containing the words collagen-induced arthritis.

  2. 11. Self reactivity and tolerance in the immune system : studies on T cells in murine type II collagen-induced arthritis

    Author : Mikael Andersson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 12. Role of environmental toxins in chronic experimental arthrithis - in search for anti-inflammatory pathways of ethanol and nicotine

    Author : Sofia Silfverswärd Lindblad; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; collagen-induced arthritis; ethanol; testosterone; nuclear factor kappa B; smoking; nicotine; NMDA; regulatory T cells;

    Abstract : Rheumatoid arthritis (RA) is a common systemic autoimmune disorder and a debilitating disease affecting 1% of the world population. The etiology of RA is an unresolved issue. Environmental factors such as alcohol intake and cigarette smoke have been described as contributing to the pathogenesis of RA. READ MORE

  5. 13. Genetic analysis of autoimmune diseases using animal models : Mapping susceptibility genes for multiple sclerosis and rheumatoid arthritis

    Author : Hai-Tao Yang; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Collagen induced arthritis CIA ; Experimental allergic encephalomyelities EAE ; Multiple sclerosis MS ; Quantitative trait loci QTL ; Rheumatoid arthritis RA ; Linkage analysis; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Autoimmune diseases such as rheumatoid arthritis and multiple sclerosis are common human diseasesaffecting 1% and 0.1% of the population respectively. These diseases are characterized by abnormal self-tolerance in the immune system and autoimmune reactions. READ MORE

  6. 14. Analysis of effector pathways in arthritis

    Author : Nandakumar Kutty Selva; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; Genetik; cytogenetics; Arthritis; mice; monoclonal antibody; collagen type II; Histology; histochemistry; cytochemistry; Histologi; tissue culture; cytokemi; histokemi; Genetics; vävnadskultur; serologi; cytogenetik; Immunology; serology;

    Abstract : Rheumatoid arthritis (RA) is a multifactorial, polygenic autoimmune disease. For effective treatment and control of RA, understanding of disease pathways and identification of genes involved are essential. Animal models are efficient tools to identify such pathogenic mechanisms and genes underlying the disease process. READ MORE

  7. 15. Modulation of Autoimmunity by Linomide treatment or interference with costimulation

    Author : Annamaria C Tellander; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; collagen-induced arthritis; CD28; CD40; antigen presenting cells; Linomide; thymocytes; cancerology; Cytologi; onkologi; cancer;

    Abstract : Linomide is a potent immunomodulator that has been shown to inhibit autoimmunity in several animal models of autoimmune disease. We have approached the cellular and molecular mechanism of Linomide by investigating its effect on thymocyte development and its capacity to modulate the expression of activation markers on antigen presenting cells (APCs). READ MORE